OLDIAS | Online Dialysis Sensor

Summary
End-stage renal disease (ESRD) is the most severe form of chronic kidney disease that is an incurable health failure. ESRD is a widespread health issue in developed countries and the patients have only two options: either receive permanent renal replacement therapy or undergo surgery to receive a kidney transplant. There are approximately 3.1 million patients worldwide suffering from ESRD that need artificial methods to replace regular kidney functions in their organism.
The main objective of the project is to validate the uremic biomarkers in a clinical research setting by developing a diagnostic medical device in the form of a novel on-line dialysis sensor that offers a unique method for the biomarker detection. At the heart of the development is technology developed by Optofluid Technologies (OFT) that is free of the flaws of current dialysis monitoring methods such as estimating only urea based biomarkers and will offer enhanced possibilities for dialysis monitoring and quality assessment. This enables the developed sensor to outperform all the current monitoring methods on the market and fully utilize the possibilities of modern dialysis methods resulting in higher treatment efficiency and ultimately disrupting the dialysis equipment market and replacing previous technologies. The market demand has been proven by attracting business inquiries from the leading dialysis equipment producers. Negotiations with selected partners are underway.
A successful commercialization will help to improve clinical decisions by clinicians leading to better treatment. Besides enhanced treatment quality, the novel OFT´s technology will significantly reduce the environmental impact of the treatment, reduce the healthcare costs of ESRD patients and improve the patients’ life-quality. In order to guarantee a successful commercialization OFT has a team of experts with previous experience in business development and medical technology.
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More information & hyperlinks
Web resources: https://cordis.europa.eu/project/id/662861
Start date: 01-03-2015
End date: 31-08-2015
Total budget - Public funding: 71 429,00 Euro - 50 000,00 Euro
Cordis data

Original description

End-stage renal disease (ESRD) is the most severe form of chronic kidney disease that is an incurable health failure. ESRD is a widespread health issue in developed countries and the patients have only two options: either receive permanent renal replacement therapy or undergo surgery to receive a kidney transplant. There are approximately 3.1 million patients worldwide suffering from ESRD that need artificial methods to replace regular kidney functions in their organism.
The main objective of the project is to validate the uremic biomarkers in a clinical research setting by developing a diagnostic medical device in the form of a novel on-line dialysis sensor that offers a unique method for the biomarker detection. At the heart of the development is technology developed by Optofluid Technologies (OFT) that is free of the flaws of current dialysis monitoring methods such as estimating only urea based biomarkers and will offer enhanced possibilities for dialysis monitoring and quality assessment. This enables the developed sensor to outperform all the current monitoring methods on the market and fully utilize the possibilities of modern dialysis methods resulting in higher treatment efficiency and ultimately disrupting the dialysis equipment market and replacing previous technologies. The market demand has been proven by attracting business inquiries from the leading dialysis equipment producers. Negotiations with selected partners are underway.
A successful commercialization will help to improve clinical decisions by clinicians leading to better treatment. Besides enhanced treatment quality, the novel OFT´s technology will significantly reduce the environmental impact of the treatment, reduce the healthcare costs of ESRD patients and improve the patients’ life-quality. In order to guarantee a successful commercialization OFT has a team of experts with previous experience in business development and medical technology.

Status

CLOSED

Call topic

PHC-12-2014-1

Update Date

26-10-2022
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Horizon 2020
H2020-EU.2. INDUSTRIAL LEADERSHIP
H2020-EU.2.3. INDUSTRIAL LEADERSHIP - Innovation In SMEs
H2020-EU.2.3.1. Mainstreaming SME support, especially through a dedicated instrument
H2020-SMEINST-1-2014
PHC-12-2014-1 Clinical research for the validation of biomarkers and/or diagnostic medical devices
H2020-EU.3. SOCIETAL CHALLENGES
H2020-EU.3.1. SOCIETAL CHALLENGES - Health, demographic change and well-being
H2020-EU.3.1.0. Cross-cutting call topics
H2020-SMEINST-1-2014
PHC-12-2014-1 Clinical research for the validation of biomarkers and/or diagnostic medical devices
H2020-EU.3.1.3. Treating and managing disease
H2020-EU.3.1.3.0. Cross-cutting call topics
H2020-SMEINST-1-2014
PHC-12-2014-1 Clinical research for the validation of biomarkers and/or diagnostic medical devices