Refeed | Customised lipid supplementation of culture media for efficient in vitro cell culture applications

Summary
Cell culturing allows scientists to grow cells under controlled conditions outside their natural environments. Each cell type requires a medium in which it can grow that is able to supply all nutrients the cells need for subsistence. Historically, cell biology has always worked on nucleic acid and proteins, leaving lipids behind. In fact, lipids have always received little consideration in academia and from biotechnology companies. Therefore, culture media manufacturers have always considered the lipid intake and its composition quality unimportant, which justifies their use of low-cost and low-quality molecules. Remembrane has proven the importance of lipids in membrane composition and properties, and have developed a sophisticated process for customising lipid supplements able to recreate a membrane environment similar to the one that cells have in-vivo. The lipid supplements are tailored to specific cell type and protocol, and are able to enhance the quality and reliability of in-vitro experimental models.
The Phase 1 project will be focused on establishing a complete scale-up strategy, including the elaboration of an industrialisation plan, a scalable business model and commercialization strategy and on planning new collaborations and partnerships with end users to build up strong successful business and use cases.
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More information & hyperlinks
Web resources: https://cordis.europa.eu/project/id/762343
Start date: 01-01-2017
End date: 30-04-2017
Total budget - Public funding: 71 429,00 Euro - 50 000,00 Euro
Cordis data

Original description

Cell culturing allows scientists to grow cells under controlled conditions outside their natural environments. Each cell type requires a medium in which it can grow that is able to supply all nutrients the cells need for subsistence. Historically, cell biology has always worked on nucleic acid and proteins, leaving lipids behind. In fact, lipids have always received little consideration in academia and from biotechnology companies. Therefore, culture media manufacturers have always considered the lipid intake and its composition quality unimportant, which justifies their use of low-cost and low-quality molecules. Remembrane has proven the importance of lipids in membrane composition and properties, and have developed a sophisticated process for customising lipid supplements able to recreate a membrane environment similar to the one that cells have in-vivo. The lipid supplements are tailored to specific cell type and protocol, and are able to enhance the quality and reliability of in-vitro experimental models.
The Phase 1 project will be focused on establishing a complete scale-up strategy, including the elaboration of an industrialisation plan, a scalable business model and commercialization strategy and on planning new collaborations and partnerships with end users to build up strong successful business and use cases.

Status

CLOSED

Call topic

SMEInst-05-2016-2017

Update Date

26-10-2022
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Horizon 2020
H2020-EU.2. INDUSTRIAL LEADERSHIP
H2020-EU.2.3. INDUSTRIAL LEADERSHIP - Innovation In SMEs
H2020-EU.2.3.1. Mainstreaming SME support, especially through a dedicated instrument
H2020-SMEINST-2-2016-2017
SMEInst-05-2016-2017 Supporting innovative SMEs in the healthcare biotechnology sector
H2020-EU.3. SOCIETAL CHALLENGES
H2020-EU.3.1. SOCIETAL CHALLENGES - Health, demographic change and well-being
H2020-EU.3.1.0. Cross-cutting call topics
H2020-SMEINST-2-2016-2017
SMEInst-05-2016-2017 Supporting innovative SMEs in the healthcare biotechnology sector
H2020-EU.3.1.3. Treating and managing disease
H2020-EU.3.1.3.0. Cross-cutting call topics
H2020-SMEINST-1-2016-2017
SMEInst-05-2016-2017 Supporting innovative SMEs in the healthcare biotechnology sector
H2020-SMEINST-2-2016-2017
SMEInst-05-2016-2017 Supporting innovative SMEs in the healthcare biotechnology sector