FIH-IO | Development of a first-in-class inhibitor of FIH for cancer immunotherapy

Summary
We plan to carry out a valorisation project for a series of novel small molecule inhibitors of Factor Inhibiting HIF (FIH) that we have developed for the treatment of lung cancer, as a next-generation therapeutic approach in the field of immuno-oncology.
The valorisation plan will include: clarification of IP rights and strategy, establishing contacts with potential investors and pharma partners, and verification of the potential of start-up creation. Moreover, valorisation activities will include progression of hits against FIH into a lead optimisation campaign with the aim of designating a candidate drug.
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More information & hyperlinks
Web resources: https://cordis.europa.eu/project/id/101069333
Start date: 01-06-2022
End date: 30-11-2023
Total budget - Public funding: - 150 000,00 Euro
Cordis data

Original description

We plan to carry out a valorisation project for a series of novel small molecule inhibitors of Factor Inhibiting HIF (FIH) that we have developed for the treatment of lung cancer, as a next-generation therapeutic approach in the field of immuno-oncology.
The valorisation plan will include: clarification of IP rights and strategy, establishing contacts with potential investors and pharma partners, and verification of the potential of start-up creation. Moreover, valorisation activities will include progression of hits against FIH into a lead optimisation campaign with the aim of designating a candidate drug.

Status

CLOSED

Call topic

ERC-2022-POC1

Update Date

09-02-2023
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Horizon Europe
HORIZON.1 Excellent Science
HORIZON.1.1 European Research Council (ERC)
HORIZON.1.1.0 Cross-cutting call topics
ERC-2022-POC1 ERC PROOF OF CONCEPT GRANTS1
HORIZON.1.1.1 Frontier science
ERC-2022-POC1 ERC PROOF OF CONCEPT GRANTS1