STENTBOT | Wireless Stent-like Soft Millirobots (STENTBOT) for Minimally Invasive Brain Vasculature Disease Treatments

Summary
Diseases in the brain vasculature, such as acute ischemic stroke, aneurysm and brain tumors, are fatal and require medical devices to treat them with minimal invasion. However, current tethered devices have limited safe access into the distal or tortuous vascular routes, which prevent saving lives of some patients. Therefore, we propose a wireless stent-shaped magnetic soft millirobot, stentbot, which would have the capability of safe access to such routes. Also, the stentbot will be able to be repositioned afterwards without repeating the same procedure fully again if the disease location changes or if the initial position of the device is observed to be not optimal. Such robot concept was originated in the ERC-AdG project of the PI. After reaching its target location safely and precisely under medical imaging and external magnetic actuation guidance, the robot will deliver the tissue plasminogen activator drugs on-demand locally to treat the acute ischemic stroke. Moreover, the robot will be used to treat aneurysms minimally invasively by becoming a flow diverter to regulate flow into the aneurysm sites.
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More information & hyperlinks
Web resources: https://cordis.europa.eu/project/id/101100727
Start date: 01-12-2022
End date: 30-04-2026
Total budget - Public funding: - 150 000,00 Euro
Cordis data

Original description

Diseases in the brain vasculature, such as acute ischemic stroke, aneurysm and brain tumors, are fatal and require medical devices to treat them with minimal invasion. However, current tethered devices have limited safe access into the distal or tortuous vascular routes, which prevent saving lives of some patients. Therefore, we propose a wireless stent-shaped magnetic soft millirobot, stentbot, which would have the capability of safe access to such routes. Also, the stentbot will be able to be repositioned afterwards without repeating the same procedure fully again if the disease location changes or if the initial position of the device is observed to be not optimal. Such robot concept was originated in the ERC-AdG project of the PI. After reaching its target location safely and precisely under medical imaging and external magnetic actuation guidance, the robot will deliver the tissue plasminogen activator drugs on-demand locally to treat the acute ischemic stroke. Moreover, the robot will be used to treat aneurysms minimally invasively by becoming a flow diverter to regulate flow into the aneurysm sites.

Status

SIGNED

Call topic

ERC-2022-POC2

Update Date

09-02-2023
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EU-Programme-Call
Horizon Europe
HORIZON.1 Excellent Science
HORIZON.1.1 European Research Council (ERC)
HORIZON.1.1.0 Cross-cutting call topics
ERC-2022-POC2 ERC PROOF OF CONCEPT GRANTS2
HORIZON.1.1.1 Frontier science
ERC-2022-POC2 ERC PROOF OF CONCEPT GRANTS2