AquaDrugs | Uncovering the effects of pharmaceuticals in the wild, beyond individuals to animal communities

Summary
The increasing production and release of pharmaceutical pollutants into waterways is now a leading threat to aquatic wildlife and ecosystems around the world. Despite this, knowledge on the hazards these contaminants cause in complex natural ecosystems is still extremely poor and thus considered an urgent research priority. AquaDrugs will harness new developments in underwater animal tracking and computer automation to identify how pharmaceutical waste in the environment can induce behavioural changes in animals that lead to high-order ecological effects. Through a series of well-integrated experiments, and using fish as a model system, AquaDrugs will trace the impact of pharmaceuticals across biological scales to address four novel and ambitious objectives: (1) test how environmentally relevant concentrations of two globally pervasive pharmaceuticals (clobazam an tramadol), both in isolation and in a mixture, influence ecologically important wildlife behaviours and variability; (2) identify whether, and how, such changes impact animal collectives; (3) determine how pharmaceutical-induced behavioural changes at the individual and group levels scale up to shape aquatic communities; and (4) uncover how exposure shapes the ecological interactions of multiple species. The project will deliver urgently needed data for chemicals regulation leading to improved policies that safeguard Europe’s aquatic ecosystems and wildlife from pharmaceutical impacts. The interdisciplinary approaches and theory in AquaDrugs—from integrative ecology, ecotoxicology, and analytical chemistry—also promises to yield pioneering results and experimental innovations that will advance these scientific fields and boost the expertise and academic career of the research fellow, Dr Marcus Michelangeli. Importantly, the research in AquaDrugs directly addresses key research priorities in Europe including the European Green Deal and the EU’s Mission for ‘Healthy Oceans, Seas, and Inland Waters’.
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More information & hyperlinks
Web resources: https://cordis.europa.eu/project/id/101061889
Start date: 01-01-2023
End date: 31-12-2024
Total budget - Public funding: - 222 727,00 Euro
Cordis data

Original description

The increasing production and release of pharmaceutical pollutants into waterways is now a leading threat to aquatic wildlife and ecosystems around the world. Despite this, knowledge on the hazards these contaminants cause in complex natural ecosystems is still extremely poor and thus considered an urgent research priority. AquaDrugs will harness new developments in underwater animal tracking and computer automation to identify how pharmaceutical waste in the environment can induce behavioural changes in animals that lead to high-order ecological effects. Through a series of well-integrated experiments, and using fish as a model system, AquaDrugs will trace the impact of pharmaceuticals across biological scales to address four novel and ambitious objectives: (1) test how environmentally relevant concentrations of two globally pervasive pharmaceuticals (clobazam an tramadol), both in isolation and in a mixture, influence ecologically important wildlife behaviours and variability; (2) identify whether, and how, such changes impact animal collectives; (3) determine how pharmaceutical-induced behavioural changes at the individual and group levels scale up to shape aquatic communities; and (4) uncover how exposure shapes the ecological interactions of multiple species. The project will deliver urgently needed data for chemicals regulation leading to improved policies that safeguard Europe’s aquatic ecosystems and wildlife from pharmaceutical impacts. The interdisciplinary approaches and theory in AquaDrugs—from integrative ecology, ecotoxicology, and analytical chemistry—also promises to yield pioneering results and experimental innovations that will advance these scientific fields and boost the expertise and academic career of the research fellow, Dr Marcus Michelangeli. Importantly, the research in AquaDrugs directly addresses key research priorities in Europe including the European Green Deal and the EU’s Mission for ‘Healthy Oceans, Seas, and Inland Waters’.

Status

SIGNED

Call topic

HORIZON-MSCA-2021-PF-01-01

Update Date

09-02-2023
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Horizon Europe
HORIZON.1 Excellent Science
HORIZON.1.2 Marie Skłodowska-Curie Actions (MSCA)
HORIZON.1.2.0 Cross-cutting call topics
HORIZON-MSCA-2021-PF-01
HORIZON-MSCA-2021-PF-01-01 MSCA Postdoctoral Fellowships 2021