Summary
Anastomotic leakage of colon content into the abdominal cavity is the most devastating complication associated with colorectal surgery. Leaks occur in ~22% of cases, leading to increased hospitalization time, higher re-operation rates, increased patient mortality & additional costs.
To minimize the risk of a leak, surgeons create a loop of the small bowel which is diverted outside the abdominal wall & connected to a stoma bag to collect patient’s feces for 4-6 months. Diverting stoma significantly diminishes patients’ quality of life, increases cost of care &
requires an additional invasive surgery to reverse the stoma. Our novel device, CG-100, is an elastic tubular sheath that is positioned at the anastomosis site during the primary colorectal surgery & creates an internal bypass for all colon content. CG-100 is removed non-surgically 10
days after primary surgery. CG-100 addresses will improve patient quality of life, save ~1350 pa lives & reduce healthcare costs by €4B pa in EU.
To minimize the risk of a leak, surgeons create a loop of the small bowel which is diverted outside the abdominal wall & connected to a stoma bag to collect patient’s feces for 4-6 months. Diverting stoma significantly diminishes patients’ quality of life, increases cost of care &
requires an additional invasive surgery to reverse the stoma. Our novel device, CG-100, is an elastic tubular sheath that is positioned at the anastomosis site during the primary colorectal surgery & creates an internal bypass for all colon content. CG-100 is removed non-surgically 10
days after primary surgery. CG-100 addresses will improve patient quality of life, save ~1350 pa lives & reduce healthcare costs by €4B pa in EU.
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More information & hyperlinks
| Web resources: | https://cordis.europa.eu/project/id/190124297 |
| Start date: | 01-06-2022 |
| End date: | 31-05-2025 |
| Total budget - Public funding: | 3 241 875,00 Euro - 2 269 312,00 Euro |
Cordis data
Original description
Anastomotic leakage of colon content into the abdominal cavity is the most devastating complication associated with colorectal surgery. Leaks occur in ~22% of cases, leading to increased hospitalization time, higher re-operation rates, increased patient mortality & additional costs.To minimize the risk of a leak, surgeons create a loop of the small bowel which is diverted outside the abdominal wall & connected to a stoma bag to collect patient’s feces for 4-6 months. Diverting stoma significantly diminishes patients’ quality of life, increases cost of care &
requires an additional invasive surgery to reverse the stoma. Our novel device, CG-100, is an elastic tubular sheath that is positioned at the anastomosis site during the primary colorectal surgery & creates an internal bypass for all colon content. CG-100 is removed non-surgically 10
days after primary surgery. CG-100 addresses will improve patient quality of life, save ~1350 pa lives & reduce healthcare costs by €4B pa in EU.
Status
SIGNEDCall topic
HORIZON-EIC-2021-ACCELERATOROPEN-01Update Date
09-02-2023
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