Summary
Heart failure (HF) represents a major public health concern, affecting around 13M people worldwide. A major risk factor for HF is a myocardial infarction, which causes ventricular remodelling, during which the ventricle enlarges, making the heart even less effective at pumping blood, and
results in displacement of the papillary muscle. Progressive papillary muscle displacement leads to severe Functional Mitral Regurgitation in about 20% of the patients, the only ones currently receiving treatment because of the severity of the condition. The remaining 80% of patients don’t
experience severe FMR and are not considered for surgery: they will continue to suffer, and likely die since there is no therapeutic option available. Cardiac Success develops the V-sling system, a transcatheter ventricular repair device to improve cardiac function in HF patients. The
objectives of the project are to finalize product optimization, complete V&V and pre-clinical testing, and perform the FIH study.
results in displacement of the papillary muscle. Progressive papillary muscle displacement leads to severe Functional Mitral Regurgitation in about 20% of the patients, the only ones currently receiving treatment because of the severity of the condition. The remaining 80% of patients don’t
experience severe FMR and are not considered for surgery: they will continue to suffer, and likely die since there is no therapeutic option available. Cardiac Success develops the V-sling system, a transcatheter ventricular repair device to improve cardiac function in HF patients. The
objectives of the project are to finalize product optimization, complete V&V and pre-clinical testing, and perform the FIH study.
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More information & hyperlinks
Web resources: | https://cordis.europa.eu/project/id/190122502 |
Start date: | 01-05-2022 |
End date: | 30-04-2026 |
Total budget - Public funding: | 8 531 525,00 Euro - 2 500 000,00 Euro |
Cordis data
Original description
Heart failure (HF) represents a major public health concern, affecting around 13M people worldwide. A major risk factor for HF is a myocardial infarction, which causes ventricular remodelling, during which the ventricle enlarges, making the heart even less effective at pumping blood, andresults in displacement of the papillary muscle. Progressive papillary muscle displacement leads to severe Functional Mitral Regurgitation in about 20% of the patients, the only ones currently receiving treatment because of the severity of the condition. The remaining 80% of patients don’t
experience severe FMR and are not considered for surgery: they will continue to suffer, and likely die since there is no therapeutic option available. Cardiac Success develops the V-sling system, a transcatheter ventricular repair device to improve cardiac function in HF patients. The
objectives of the project are to finalize product optimization, complete V&V and pre-clinical testing, and perform the FIH study.
Status
SIGNEDCall topic
HORIZON-EIC-2021-ACCELERATOROPEN-01Update Date
09-02-2023
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