TriScanner | Next-gen fluorescence imaging for research and theranostics

Summary
Fluorescence microscopy is key technique in the life sciences, though the method struggles to deliver the fast and sensitive imaging of multicellular systems. Such samples are now becoming commonplace not only in research but also in clinical use, including spatially-resolved 'omics' and theranostics based on patient material that allow the development of personalized treatments. However, their general uptake is limited by the absence of suitable instrumentation.

As part of our ERC-funded research, we have invented the TriScanner, a novel fluorescence microscope that offers transformative imaging performance (much faster imaging, higher resolution, higher sensitivity), and is also simple, robust, and affordable. Our TriScanner readily addresses an urgent need in current research and healthcare research, and is well-positioned to scale out from research into 'workhorse' usage in industrial R&D and diagnostics.

We propose to develop this idea from a concept and lab prototype into a robust demonstrator that is showcased on a variety of highly-relevant applications, and that we will leverage to raise user awareness and interact with key leaders in academia and leading commercial partners. This project will furthermore allow us to explore the business case and market potential, in view of developing and selecting the optimal valorization track. We expect to deliver societal impact by providing unprecedented new imaging capabilities in a fast-moving and highly influential research field.
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More information & hyperlinks
Web resources: https://cordis.europa.eu/project/id/101113439
Start date: 01-06-2023
End date: 30-11-2024
Total budget - Public funding: - 150 000,00 Euro
Cordis data

Original description

Fluorescence microscopy is key technique in the life sciences, though the method struggles to deliver the fast and sensitive imaging of multicellular systems. Such samples are now becoming commonplace not only in research but also in clinical use, including spatially-resolved 'omics' and theranostics based on patient material that allow the development of personalized treatments. However, their general uptake is limited by the absence of suitable instrumentation.

As part of our ERC-funded research, we have invented the TriScanner, a novel fluorescence microscope that offers transformative imaging performance (much faster imaging, higher resolution, higher sensitivity), and is also simple, robust, and affordable. Our TriScanner readily addresses an urgent need in current research and healthcare research, and is well-positioned to scale out from research into 'workhorse' usage in industrial R&D and diagnostics.

We propose to develop this idea from a concept and lab prototype into a robust demonstrator that is showcased on a variety of highly-relevant applications, and that we will leverage to raise user awareness and interact with key leaders in academia and leading commercial partners. This project will furthermore allow us to explore the business case and market potential, in view of developing and selecting the optimal valorization track. We expect to deliver societal impact by providing unprecedented new imaging capabilities in a fast-moving and highly influential research field.

Status

SIGNED

Call topic

ERC-2022-POC2

Update Date

31-07-2023
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Horizon Europe
HORIZON.1 Excellent Science
HORIZON.1.1 European Research Council (ERC)
HORIZON.1.1.0 Cross-cutting call topics
ERC-2022-POC2 ERC PROOF OF CONCEPT GRANTS2
HORIZON.1.1.1 Frontier science
ERC-2022-POC2 ERC PROOF OF CONCEPT GRANTS2