Summary
Over 2.7 million people in the EU were diagnosed with cancer in 2020, while 1.3 million people lost their lives to it. Cancer cases are
predicted to increase by 24% by 2035, making it the leading cause of death in the EU. The current leading specific molecular imaging
diagnostic technique sensitive to cancer is based on Positron Emission Tomography (PET). Due to the high implementation cost of
PET, this high-sensitivity diagnostics, is only available to less than 0,5 % of the medical centers in the world. The critical component of
the overall cost is the cost of PET scanners. Our project proposes a radical vision to translate European breakthrough technological
advances in Time-of-Flight PET detection to a revolutionary, fully modular, cost-accessible flexible family of devices for
applications from the standard PET center to the surgery, epilepsy clinics, intensive care units and even emergency rooms and in
mobile units installed in vans. The proposed PetVision project aims to develop a simple pilot demonstrator, a modular panel PET device with a coincidence timing resolution of about 75 ps FWHM, close to the intrinsic timing limit of currently available PET scintillators. This resolution is several times better than the current gold standard of 214 ps FWHM achieved with the current clinical state-of-the-art device (Siemens Biograph Vision). With such excellent timing, the panel detectors can cover only a limited solid angle to reach the same sensitivity or improve the sensitivity in the case of a total-body imager. For the realization of the device, a package of breakthrough innovations in detector design, photo-sensor, and front-end electronics are planned. We expect that the proposed device will dramatically impact human health.
predicted to increase by 24% by 2035, making it the leading cause of death in the EU. The current leading specific molecular imaging
diagnostic technique sensitive to cancer is based on Positron Emission Tomography (PET). Due to the high implementation cost of
PET, this high-sensitivity diagnostics, is only available to less than 0,5 % of the medical centers in the world. The critical component of
the overall cost is the cost of PET scanners. Our project proposes a radical vision to translate European breakthrough technological
advances in Time-of-Flight PET detection to a revolutionary, fully modular, cost-accessible flexible family of devices for
applications from the standard PET center to the surgery, epilepsy clinics, intensive care units and even emergency rooms and in
mobile units installed in vans. The proposed PetVision project aims to develop a simple pilot demonstrator, a modular panel PET device with a coincidence timing resolution of about 75 ps FWHM, close to the intrinsic timing limit of currently available PET scintillators. This resolution is several times better than the current gold standard of 214 ps FWHM achieved with the current clinical state-of-the-art device (Siemens Biograph Vision). With such excellent timing, the panel detectors can cover only a limited solid angle to reach the same sensitivity or improve the sensitivity in the case of a total-body imager. For the realization of the device, a package of breakthrough innovations in detector design, photo-sensor, and front-end electronics are planned. We expect that the proposed device will dramatically impact human health.
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More information & hyperlinks
| Web resources: | https://cordis.europa.eu/project/id/101099896 |
| Start date: | 01-09-2023 |
| End date: | 31-08-2028 |
| Total budget - Public funding: | 3 374 041,25 Euro - 3 374 041,00 Euro |
Cordis data
Original description
Over 2.7 million people in the EU were diagnosed with cancer in 2020, while 1.3 million people lost their lives to it. Cancer cases arepredicted to increase by 24% by 2035, making it the leading cause of death in the EU. The current leading specific molecular imaging
diagnostic technique sensitive to cancer is based on Positron Emission Tomography (PET). Due to the high implementation cost of
PET, this high-sensitivity diagnostics, is only available to less than 0,5 % of the medical centers in the world. The critical component of
the overall cost is the cost of PET scanners. Our project proposes a radical vision to translate European breakthrough technological
advances in Time-of-Flight PET detection to a revolutionary, fully modular, cost-accessible flexible family of devices for
applications from the standard PET center to the surgery, epilepsy clinics, intensive care units and even emergency rooms and in
mobile units installed in vans. The proposed PetVision project aims to develop a simple pilot demonstrator, a modular panel PET device with a coincidence timing resolution of about 75 ps FWHM, close to the intrinsic timing limit of currently available PET scintillators. This resolution is several times better than the current gold standard of 214 ps FWHM achieved with the current clinical state-of-the-art device (Siemens Biograph Vision). With such excellent timing, the panel detectors can cover only a limited solid angle to reach the same sensitivity or improve the sensitivity in the case of a total-body imager. For the realization of the device, a package of breakthrough innovations in detector design, photo-sensor, and front-end electronics are planned. We expect that the proposed device will dramatically impact human health.
Status
SIGNEDCall topic
HORIZON-EIC-2022-PATHFINDEROPEN-01-01Update Date
31-07-2023
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Organisations
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| INSTITUT JOZEF STEFAN (Coördinator)
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| AGENCIA ESTATAL CONSEJO SUPERIOR DE INVESTIGACIONES CIENTIFICAS
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| FONDAZIONE BRUNO KESSLER
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| GENERAL EQUIPMENT FOR MEDICAL IMAGING SA
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| KLINIKUM RECHTS DER ISAR DER TECHNISCHEN UNIVERSITAT MUNCHEN
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| THE GENERAL HOSPITAL CORPORATION
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| UNIVERSITAT DE BARCELONA