METAflow | Development and validation of the first digital, clinical grade flow cytometry platform for enhanced diagnosis accuracy and sustainability in immunology and hemato oncology

Summary
After successful development of METAglut1, an IVD Medical Device for diagnosis of the Glut1 Deficiency Syndrome ( available for clinical use), we are currently focused on developing a new breakthrough solution: METAflow. Flow cytometry (FC) is a powerful tool widely use in research. However, the high cost and complexity of interpretation of FC data hampers its full clinical exploitation. Main pain-points of clinical FC data analysis, include need for manual analysis, which is accompanied by complexity with increasing number of dimensions, lack of robustness and limited scale-up. The lack of automated analytical process stems from dearth of robust algorithms, limited regulatory compliance and need for considerable coding skills. With METAflow we bring to the market the first digital, clinical grade FC platform, which offers comprehensive data analysis, robustness, and usability, addressing the “lost in translational research” issue of flow cytometry in the clinics.
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Web resources: https://cordis.europa.eu/project/id/190166506
Start date: 01-01-2023
End date: 30-06-2024
Total budget - Public funding: 3 570 827,50 Euro - 2 499 579,00 Euro
Cordis data

Original description

After successful development of METAglut1, an IVD Medical Device for diagnosis of the Glut1 Deficiency Syndrome ( available for clinical use), we are currently focused on developing a new breakthrough solution: METAflow. Flow cytometry (FC) is a powerful tool widely use in research. However, the high cost and complexity of interpretation of FC data hampers its full clinical exploitation. Main pain-points of clinical FC data analysis, include need for manual analysis, which is accompanied by complexity with increasing number of dimensions, lack of robustness and limited scale-up. The lack of automated analytical process stems from dearth of robust algorithms, limited regulatory compliance and need for considerable coding skills. With METAflow we bring to the market the first digital, clinical grade FC platform, which offers comprehensive data analysis, robustness, and usability, addressing the “lost in translational research” issue of flow cytometry in the clinics.

Status

SIGNED

Call topic

HORIZON-EIC-2022-ACCELERATOROPEN-01

Update Date

31-07-2023
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Horizon Europe
HORIZON.3 Innovative Europe
HORIZON.3.1 The European Innovation Council (EIC)
HORIZON.3.1.0 Cross-cutting call topics
HORIZON-EIC-2022-ACCELERATOR-01
HORIZON-EIC-2022-ACCELERATOROPEN-01 EIC Accelerator Open