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CelerisTx - Celeris One Platform | Closed-loop deep learning in early-stage drug discovery - cloud platform for targeted protein degradation

Summary
Celeris Therapeutics is a deep learning company that uses innovative, in-silico methods such as geometric deep learning and graph neural networks to degrade currently undruggable targets (pathogenic proteins). The platform shall make a broad impact by addressing currently incureable diseases such as Alzheimer's, Parkinson's, and different types of cancer like breast and prostate cancer.

Celeris Therapeutics' technical solution is the web application (orchestration platform) Celeris One.
It consists of three modules: Hades (target ID), Xanthos (predicting biomolecular interactions and ligand design), Hephaistos (automated synthesize and validate).
The addressed market is in the early-stage drug discovery and users are pharmaceutical and biotech companies with a focus on Targeted Protein Degradation.
The targeted customers are med. and comp. chemists, that currently rely on docking, which is computationally intensive, slow and inaccurate compared to CelerisTx deep learning methods.
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More information & hyperlinks
Web resources: https://cordis.europa.eu/project/id/190126641
Start date: 01-07-2022
End date: 29-02-2024
Total budget - Public funding: 4 860 501,25 Euro - 2 500 000,00 Euro
Cordis data

Original description

Celeris Therapeutics is a deep learning company that uses innovative, in-silico methods such as geometric deep learning and graph neural networks to degrade currently undruggable targets (pathogenic proteins). The platform shall make a broad impact by addressing currently incureable diseases such as Alzheimer's, Parkinson's, and different types of cancer like breast and prostate cancer.

Celeris Therapeutics' technical solution is the web application (orchestration platform) Celeris One.
It consists of three modules: Hades (target ID), Xanthos (predicting biomolecular interactions and ligand design), Hephaistos (automated synthesize and validate).
The addressed market is in the early-stage drug discovery and users are pharmaceutical and biotech companies with a focus on Targeted Protein Degradation.
The targeted customers are med. and comp. chemists, that currently rely on docking, which is computationally intensive, slow and inaccurate compared to CelerisTx deep learning methods.

Status

SIGNED

Call topic

HORIZON-EIC-2022-ACCELERATORCHALLENGES-01

Update Date

31-07-2023
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Horizon Europe
HORIZON.3 Innovative Europe
HORIZON.3.1 The European Innovation Council (EIC)
HORIZON.3.1.0 Cross-cutting call topics
HORIZON-EIC-2022-ACCELERATOR-01
HORIZON-EIC-2022-ACCELERATORCHALLENGES-01 EIC Accelerator Challenge: Technologies for Open Strategic Autonomy