Summary
Using patented fluid management technologies, the Mera system has the ability to culture, drug & stain 3D tissues on a large scale while monitoring everything in real time, through a fully automated florescent microscope. 3D microtissues are added to a dedicated consumable bio-plate. The plate is then integrated into the main Mera system. A chemical cocktail can be introduced to selected wells on a plate in order to mature the cells into different tissue types such as liver, heart, neuronal or cancer. The fluid pathway can be changed to allow the introduction of a drug or stain to batches of multiple different tissue types. The fluid can then be recirculated, replicating the conditions in the human body where organs interact with each other. The whole process can be monitored using the automated microscope in wide field or florescent modes. The system is modular & scalable, allowing a single unit to run up to 800 microtissues simultaneously.
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More information & hyperlinks
| Web resources: | https://cordis.europa.eu/project/id/190178224 |
| Start date: | 01-10-2023 |
| End date: | 30-09-2025 |
| Total budget - Public funding: | 4 158 818,75 Euro - 2 499 999,00 Euro |
Cordis data
Original description
Using patented fluid management technologies, the Mera system has the ability to culture, drug & stain 3D tissues on a large scale while monitoring everything in real time, through a fully automated florescent microscope. 3D microtissues are added to a dedicated consumable bio-plate. The plate is then integrated into the main Mera system. A chemical cocktail can be introduced to selected wells on a plate in order to mature the cells into different tissue types such as liver, heart, neuronal or cancer. The fluid pathway can be changed to allow the introduction of a drug or stain to batches of multiple different tissue types. The fluid can then be recirculated, replicating the conditions in the human body where organs interact with each other. The whole process can be monitored using the automated microscope in wide field or florescent modes. The system is modular & scalable, allowing a single unit to run up to 800 microtissues simultaneously.Status
SIGNEDCall topic
HORIZON-EIC-2023-ACCELERATOROPEN-01Update Date
12-03-2024
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