FASTWIRE | Transformational crossing system to prevent amputation and treat complex chronic total occlusions in critical limb ischemia

Summary
Critical limb Threatening ischemia (CLTI) is caused by chronic total occlusions (CTOs) in the arteries of the lower extremities. Left untreated, the complications of CLTI results in amputation of the affected limb. The prognosis for those diagnosed with CLTI is comparative to an aggressive cancer. At 1 year post diagnosis, 25% of patients will die and 30% had an amputation, 60% are dead by year 5

CTO is caused by the build-up and calcification of plaque inside the artery, blocking the artery and hardens over time and prevents the passage of a guidewire or therapy device through the vessel. Versono has designed and developed a solution to allow an endovascular surgeon to confidently cross 90% of occlusions within 10 mins

This dedicated CTO guidewire uses an acoustic wave (ultrasound) to penetrate through the calcium/plaque and enable physicians to apply other treatments like stents, balloons or atherectomy devices to unblock the CTO and restore blood flow to the tissue downstream.
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More information & hyperlinks
Web resources: https://cordis.europa.eu/project/id/190154620
Start date: 01-03-2023
End date: 31-10-2024
Total budget - Public funding: 3 544 625,00 Euro - 2 478 175,00 Euro
Cordis data

Original description

Critical limb Threatening ischemia (CLTI) is caused by chronic total occlusions (CTOs) in the arteries of the lower extremities. Left untreated, the complications of CLTI results in amputation of the affected limb. The prognosis for those diagnosed with CLTI is comparative to an aggressive cancer. At 1 year post diagnosis, 25% of patients will die and 30% had an amputation, 60% are dead by year 5

CTO is caused by the build-up and calcification of plaque inside the artery, blocking the artery and hardens over time and prevents the passage of a guidewire or therapy device through the vessel. Versono has designed and developed a solution to allow an endovascular surgeon to confidently cross 90% of occlusions within 10 mins

This dedicated CTO guidewire uses an acoustic wave (ultrasound) to penetrate through the calcium/plaque and enable physicians to apply other treatments like stents, balloons or atherectomy devices to unblock the CTO and restore blood flow to the tissue downstream.

Status

SIGNED

Call topic

HORIZON-EIC-2023-ACCELERATOROPEN-01

Update Date

12-03-2024
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Horizon Europe
HORIZON.3 Innovative Europe
HORIZON.3.1 The European Innovation Council (EIC)
HORIZON.3.1.0 Cross-cutting call topics
HORIZON-EIC-2023-ACCELERATOR-01
HORIZON-EIC-2023-ACCELERATOROPEN-01 EIC Accelerator Open 2023