ABACUSS | AGING AND BALANCE CONTROL DURING STAIR AND STEP NEGOTIATION

Summary
Age-related loss of physical ability and balance control are important predictors for falls in older people. Activities of daily life, such as stair negotiation, are challenging as they require older people to operate close to their functional limits. This makes stair negotiation performance a good candidate to detect early-onset deterioration before a fall occurs, as well as a good task-specific exercise modality. To investigate these assumptions, I will first assess the sensitivity of linear and non-linear analyses of data from body-worn inertial measurement units (IMUs) to detect age-related and training-induced changes in balance control of older people (65+ years). These findings will then be applied to assess improvements of balance control and the underlying changes in neuromuscular organisation following a 1-year home-based stair climbing exercise program in older people. Finally, I aim to elucidate the role of cortical involvement in neuromuscular organisation during stair negotiation in older people using electroencephalograms and analyses of muscle synergies obtain from electromyographic signals of the lower limb muscles. This will allow me to assess the level of cortico-synergy coherence and the plastic changes associated with training-induced adaptations in kinematic profiles during stair negotiation. The findings from this project will contribute to a better understanding of age-related and training-induced adaptations in balance control, neuromuscular organisation, and the role of cortical involvement in task-specific adaptations. In addition, the assessments of sensitivity of current and novel analyses of inertial data will help to improve detection of early-onset deterioration of balance performance to better target training interventions at individuals with increased fall risk.
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More information & hyperlinks
Web resources: https://cordis.europa.eu/project/id/101106488
Start date: 01-08-2024
End date: 31-07-2027
Total budget - Public funding: - 270 829,00 Euro
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Original description

Age-related loss of physical ability and balance control are important predictors for falls in older people. Activities of daily life, such as stair negotiation, are challenging as they require older people to operate close to their functional limits. This makes stair negotiation performance a good candidate to detect early-onset deterioration before a fall occurs, as well as a good task-specific exercise modality. To investigate these assumptions, I will first assess the sensitivity of linear and non-linear analyses of data from body-worn inertial measurement units (IMUs) to detect age-related and training-induced changes in balance control of older people (65+ years). These findings will then be applied to assess improvements of balance control and the underlying changes in neuromuscular organisation following a 1-year home-based stair climbing exercise program in older people. Finally, I aim to elucidate the role of cortical involvement in neuromuscular organisation during stair negotiation in older people using electroencephalograms and analyses of muscle synergies obtain from electromyographic signals of the lower limb muscles. This will allow me to assess the level of cortico-synergy coherence and the plastic changes associated with training-induced adaptations in kinematic profiles during stair negotiation. The findings from this project will contribute to a better understanding of age-related and training-induced adaptations in balance control, neuromuscular organisation, and the role of cortical involvement in task-specific adaptations. In addition, the assessments of sensitivity of current and novel analyses of inertial data will help to improve detection of early-onset deterioration of balance performance to better target training interventions at individuals with increased fall risk.

Status

SIGNED

Call topic

HORIZON-MSCA-2022-PF-01-01

Update Date

12-03-2024
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Horizon Europe
HORIZON.1 Excellent Science
HORIZON.1.2 Marie Skłodowska-Curie Actions (MSCA)
HORIZON.1.2.0 Cross-cutting call topics
HORIZON-MSCA-2022-PF-01
HORIZON-MSCA-2022-PF-01-01 MSCA Postdoctoral Fellowships 2022