hiPSCmore | Instrumented human stem cells to see more during high throughput screening in drugInstrumented human stem cells to see more during high throughput screening in drug discovery and regenerative medicine

Summary
"In hiPSCmore (read hiP-See-More), my team and I will engineer fluorescent sensors in the DNA of human induced pluripotent stem cells (hiPSC) so we can “See More” during high-throughput imaging screenings (imHTS) for drug discovery and regenerative medicine.

Since hiPSCs can differentiate in most cell types in the human body, they are the ideal cell source for more predictively screening therapies. Yet, hiPSCs are expensive to maintain and require external reagents to visualize pathophysiological changes, which adds to the screening cost and complexity. In fact, the major hurdle in adopting hiPSCs for imHTS has been the price increase from
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More information & hyperlinks
Web resources: https://cordis.europa.eu/project/id/101158039
Start date: 01-05-2024
End date: 31-10-2025
Total budget - Public funding: - 150 000,00 Euro
Cordis data

Original description

"In hiPSCmore (read hiP-See-More), my team and I will engineer fluorescent sensors in the DNA of human induced pluripotent stem cells (hiPSC) so we can “See More” during high-throughput imaging screenings (imHTS) for drug discovery and regenerative medicine.

Since hiPSCs can differentiate in most cell types in the human body, they are the ideal cell source for more predictively screening therapies. Yet, hiPSCs are expensive to maintain and require external reagents to visualize pathophysiological changes, which adds to the screening cost and complexity. In fact, the major hurdle in adopting hiPSCs for imHTS has been the price increase from

Status

SIGNED

Call topic

ERC-2023-POC

Update Date

12-03-2024
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Horizon Europe
HORIZON.1 Excellent Science
HORIZON.1.1 European Research Council (ERC)
HORIZON.1.1.0 Cross-cutting call topics
ERC-2023-POC ERC PROOF OF CONCEPT GRANTS
HORIZON.1.1.1 Frontier science
ERC-2023-POC ERC PROOF OF CONCEPT GRANTS