GNVISION | Gamma-Neutron Vision aimed at improved cancer treatments in Hadron Therapy

Summary
Proton therapy represents one of the most recent and adavanced tools in cancer treatment, especially for complex cases and pediatric patients. Despite its exponential deployment worldwide, hadron therapy still faces two main limitations, which are related to: i) accurate ion-range verification and ii) assessment of the secondary (unwanted) neutron dose. The present proposal presents an innovative tool, that can help to improve this situation and thus increase the potential benefits of hadron therapy. This project focuses on a portable device, that can simultaneously image both gamma-rays and thermal neutrons, which are ineluctably produced during the treatment. On one hand, imaging thermal neutrons may help to quantify more reliably the secondary neutron dose received by the patient during therapy. Complementary gamma-ray imaging is accomplished with the same apparatus by means of electronic collimation, thus enabling real-time assessment of the ion-range. In terms of gamma-vision, the system has been recently tested in pre-clinical conditions at CNA-Seville and HIT-Heidelberg. This POC project aims therefore at demonstrating the additional neutron-vision capability, thereby elevating the full GNVision system to TRL6, and addressing its commercial viability in the health-sector.
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More information & hyperlinks
Web resources: https://cordis.europa.eu/project/id/101113330
Start date: 01-01-2024
End date: 30-06-2025
Total budget - Public funding: - 150 000,00 Euro
Cordis data

Original description

Proton therapy represents one of the most recent and adavanced tools in cancer treatment, especially for complex cases and pediatric patients. Despite its exponential deployment worldwide, hadron therapy still faces two main limitations, which are related to: i) accurate ion-range verification and ii) assessment of the secondary (unwanted) neutron dose. The present proposal presents an innovative tool, that can help to improve this situation and thus increase the potential benefits of hadron therapy. This project focuses on a portable device, that can simultaneously image both gamma-rays and thermal neutrons, which are ineluctably produced during the treatment. On one hand, imaging thermal neutrons may help to quantify more reliably the secondary neutron dose received by the patient during therapy. Complementary gamma-ray imaging is accomplished with the same apparatus by means of electronic collimation, thus enabling real-time assessment of the ion-range. In terms of gamma-vision, the system has been recently tested in pre-clinical conditions at CNA-Seville and HIT-Heidelberg. This POC project aims therefore at demonstrating the additional neutron-vision capability, thereby elevating the full GNVision system to TRL6, and addressing its commercial viability in the health-sector.

Status

SIGNED

Call topic

ERC-2022-POC2

Update Date

12-03-2024
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Horizon Europe
HORIZON.1 Excellent Science
HORIZON.1.1 European Research Council (ERC)
HORIZON.1.1.0 Cross-cutting call topics
ERC-2022-POC2 ERC PROOF OF CONCEPT GRANTS2
HORIZON.1.1.1 Frontier science
ERC-2022-POC2 ERC PROOF OF CONCEPT GRANTS2