grabRNA | Smart RNA delivery for therapy and diagnostic

Summary
The progression of RNA-based cellular applications in molecular therapy has been greatly hindered due the difficulty of delivering RNA across biological barriers. Interest has therefore grown in the development of carrier systems which can facilitate RNA delivery in a controlled manner. Herein, we use peptide-based, binders to stabilise and deliver double-stranded RNA. The main goals of this project are the identification of lead candidates with robust cell delivery in relevant cell lines, and to be fit for partnering with a company and/or securing follow-up resources.
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More information & hyperlinks
Web resources: https://cordis.europa.eu/project/id/101112973
Start date: 01-04-2023
End date: 30-09-2024
Total budget - Public funding: - 150 000,00 Euro
Cordis data

Original description

The progression of RNA-based cellular applications in molecular therapy has been greatly hindered due the difficulty of delivering RNA across biological barriers. Interest has therefore grown in the development of carrier systems which can facilitate RNA delivery in a controlled manner. Herein, we use peptide-based, binders to stabilise and deliver double-stranded RNA. The main goals of this project are the identification of lead candidates with robust cell delivery in relevant cell lines, and to be fit for partnering with a company and/or securing follow-up resources.

Status

SIGNED

Call topic

ERC-2022-POC2

Update Date

12-03-2024
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