Summary
The progression of RNA-based cellular applications in molecular therapy has been greatly hindered due the difficulty of delivering RNA across biological barriers. Interest has therefore grown in the development of carrier systems which can facilitate RNA delivery in a controlled manner. Herein, we use peptide-based, binders to stabilise and deliver double-stranded RNA. The main goals of this project are the identification of lead candidates with robust cell delivery in relevant cell lines, and to be fit for partnering with a company and/or securing follow-up resources.
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| Web resources: | https://cordis.europa.eu/project/id/101112973 |
| Start date: | 01-04-2023 |
| End date: | 30-09-2024 |
| Total budget - Public funding: | - 150 000,00 Euro |
Cordis data
Original description
The progression of RNA-based cellular applications in molecular therapy has been greatly hindered due the difficulty of delivering RNA across biological barriers. Interest has therefore grown in the development of carrier systems which can facilitate RNA delivery in a controlled manner. Herein, we use peptide-based, binders to stabilise and deliver double-stranded RNA. The main goals of this project are the identification of lead candidates with robust cell delivery in relevant cell lines, and to be fit for partnering with a company and/or securing follow-up resources.Status
SIGNEDCall topic
ERC-2022-POC2Update Date
12-03-2024
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