TimeNanoLive | Time-based single molecule nanolocalization for live cell imaging

Summary
Despite the tremendous advances in single molecule localization microscopy mainly obtained on fixed cells, a major step is highly needed to transform it into a genuine live-cell nanoscopy allowing to understand biological processes in their full multi-scale nature from the individual molecule, to the cell, to the multicellular tissues. Currently, there is no solution to image with an acquisition speed compatible with the dynamics of living cells (>kHz), over a large volumes (>10000 μm3), with a significant in-depth imaging capability (>10 µm) without compromising the resolution (
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More information & hyperlinks
Web resources: https://cordis.europa.eu/project/id/101098103
Start date: 01-11-2023
End date: 31-10-2028
Total budget - Public funding: 2 498 196,00 Euro - 2 498 196,00 Euro
Cordis data

Original description

Despite the tremendous advances in single molecule localization microscopy mainly obtained on fixed cells, a major step is highly needed to transform it into a genuine live-cell nanoscopy allowing to understand biological processes in their full multi-scale nature from the individual molecule, to the cell, to the multicellular tissues. Currently, there is no solution to image with an acquisition speed compatible with the dynamics of living cells (>kHz), over a large volumes (>10000 μm3), with a significant in-depth imaging capability (>10 µm) without compromising the resolution (

Status

SIGNED

Call topic

ERC-2022-ADG

Update Date

12-03-2024
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Horizon Europe
HORIZON.1 Excellent Science
HORIZON.1.1 European Research Council (ERC)
HORIZON.1.1.0 Cross-cutting call topics
ERC-2022-ADG
HORIZON.1.1.1 Frontier science
ERC-2022-ADG