NanoPP | Large Scale Protein Library Screening Biosensor

Summary
In this application a platform is proposed that builds on preliminary work from ERC starting grant NanoP in order to develop a technology for high throughput electronic recognition of a large library of proteins using nanometer sized channels. These channel (or nanopore) dimensions are on the same order of magnitude as the proteins that we are using, making a natural confinement mechanism. Importantly, this allows for the efficient detection and screening of individual protein molecules and as will be shown in a high throughput manner. Here we propose to couple protein recognition to an electrical readout via a nanopore, that will result in improved prospects in efficiency, scalability, and sensitivity. Furthermore, this grant will allow for appropriate market research and IP landscaping to be performed in order to ensure the preferred option of setting up a spin-out company will be positioned correctly to ensure success.
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More information & hyperlinks
Web resources: https://cordis.europa.eu/project/id/677677
Start date: 01-01-2016
End date: 30-06-2017
Total budget - Public funding: 149 990,00 Euro - 149 990,00 Euro
Cordis data

Original description

In this application a platform is proposed that builds on preliminary work from ERC starting grant NanoP in order to develop a technology for high throughput electronic recognition of a large library of proteins using nanometer sized channels. These channel (or nanopore) dimensions are on the same order of magnitude as the proteins that we are using, making a natural confinement mechanism. Importantly, this allows for the efficient detection and screening of individual protein molecules and as will be shown in a high throughput manner. Here we propose to couple protein recognition to an electrical readout via a nanopore, that will result in improved prospects in efficiency, scalability, and sensitivity. Furthermore, this grant will allow for appropriate market research and IP landscaping to be performed in order to ensure the preferred option of setting up a spin-out company will be positioned correctly to ensure success.

Status

CLOSED

Call topic

ERC-PoC-2015

Update Date

27-04-2024
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Horizon 2020
H2020-EU.1. EXCELLENT SCIENCE
H2020-EU.1.1. EXCELLENT SCIENCE - European Research Council (ERC)
ERC-2015
ERC-2015-PoC
ERC-PoC-2015 ERC Proof of Concept Grant