UNMOVED | Simultaneous three dimensional multiphoton microscopy without mechanical depth scanning

Summary
Information in the nervous system is typically represented in activity patterns distributed across large populations of neurons in three dimensions, and there is a lot of current interest in the development of systems that can volumetrically image these patterns (or other distributed processes) in real-time. During our work towards imaging responses to artificial retinal stimulation we have developed a solution for remotely manipulating the illumination plane during temporal-focusing multiphoton imaging (a powerful bio-microscopy and photo-manipulation modality). This technique and its variations could provide unprecedented access into rapid 3D imaging at an exciting time for the neuroimaging field, where major initiatives for high-resolution brain activity mapping have been launched, and could potentially also be applied towards innovative approaches to micro-endoscopy and other applications.
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More information & hyperlinks
Web resources: https://cordis.europa.eu/project/id/641171
Start date: 01-02-2015
End date: 31-07-2016
Total budget - Public funding: 150 000,00 Euro - 150 000,00 Euro
Cordis data

Original description

Information in the nervous system is typically represented in activity patterns distributed across large populations of neurons in three dimensions, and there is a lot of current interest in the development of systems that can volumetrically image these patterns (or other distributed processes) in real-time. During our work towards imaging responses to artificial retinal stimulation we have developed a solution for remotely manipulating the illumination plane during temporal-focusing multiphoton imaging (a powerful bio-microscopy and photo-manipulation modality). This technique and its variations could provide unprecedented access into rapid 3D imaging at an exciting time for the neuroimaging field, where major initiatives for high-resolution brain activity mapping have been launched, and could potentially also be applied towards innovative approaches to micro-endoscopy and other applications.

Status

CLOSED

Call topic

ERC-PoC-2014

Update Date

27-04-2024
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Geographical location(s)
Structured mapping
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Horizon 2020
H2020-EU.1. EXCELLENT SCIENCE
H2020-EU.1.1. EXCELLENT SCIENCE - European Research Council (ERC)
ERC-2014
ERC-2014-PoC
ERC-PoC-2014 ERC Proof of Concept Grant