MetTraC | Biocatalytic Methyltransferase Cascades

Summary
The goal of this project is to develop a general system for preparative enzyme-catalyzed methylation reactions. Selective methylation of complex molecules can be challenging for synthetic chemistry. Given the exquisite chemo-, regio- and stereoselectivities of enzyme catalysis we believe that biocatalysis presents a powerful alternative for commercial production of pharmaceuticals and fine chemicals. In this project we demonstrate the applicability and commercial viability of a novel enzyme-based technology to preparative methylation reactions.
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More information & hyperlinks
Web resources: https://cordis.europa.eu/project/id/840243
Start date: 01-03-2019
End date: 31-08-2020
Total budget - Public funding: 149 760,00 Euro - 149 760,00 Euro
Cordis data

Original description

The goal of this project is to develop a general system for preparative enzyme-catalyzed methylation reactions. Selective methylation of complex molecules can be challenging for synthetic chemistry. Given the exquisite chemo-, regio- and stereoselectivities of enzyme catalysis we believe that biocatalysis presents a powerful alternative for commercial production of pharmaceuticals and fine chemicals. In this project we demonstrate the applicability and commercial viability of a novel enzyme-based technology to preparative methylation reactions.

Status

CLOSED

Call topic

ERC-2018-PoC

Update Date

27-04-2024
Geographical location(s)
Structured mapping
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EU-Programme-Call
Horizon 2020
H2020-EU.1. EXCELLENT SCIENCE
H2020-EU.1.1. EXCELLENT SCIENCE - European Research Council (ERC)
ERC-2018
ERC-2018-PoC