HydroLieve | A long-lasting non-migrating hydrogel for relieving chronic pain

Summary
Chronic Neuropathic Pain (NeP) is an enormous problem globally. Estimates predicate that 20% of adults suffer from pain world-wide and 10% are newly diagnosed with chronic pain annually1. According to the EuroPain Innovative Medicines Initiative (IMI)2, one in five adults in Europe suffers from chronic pain. One type of Neuropathic Pain that is particularly detrimental to patients quality of life is Trigeminal Neuralgia (TN). The trigeminal nerve is responsible for facial sensory function, and trauma to this nerve can result in sudden, severe, stabbing and recurrent episodes of pain. Patients with TN experience a prolonged debilitating condition, where the pain is often described as one of the most painful conditions in medicine. TN is infamously called the “suicide disease” as there have been numerous suicide reports associated with the condition. Epidemiologists estimated the prevalence of chronic TN pain is also large at 7%3, which amounts to 36 million Europeans. Similarly, in the US, the American Association of Neurological Surgeons report that 150,000 people are diagnosed with TN every year with a prevalence of chronic TN impacting 1.7 % of population 4. Therefore in this proposal, we describe the development of a long-lasting and drug-free treatment for chronic Trigeminal Neuralgia.
Unfold all
/
Fold all
More information & hyperlinks
Web resources: https://cordis.europa.eu/project/id/812792
Start date: 01-08-2018
End date: 31-12-2020
Total budget - Public funding: 149 953,75 Euro - 149 953,00 Euro
Cordis data

Original description

Chronic Neuropathic Pain (NeP) is an enormous problem globally. Estimates predicate that 20% of adults suffer from pain world-wide and 10% are newly diagnosed with chronic pain annually1. According to the EuroPain Innovative Medicines Initiative (IMI)2, one in five adults in Europe suffers from chronic pain. One type of Neuropathic Pain that is particularly detrimental to patients quality of life is Trigeminal Neuralgia (TN). The trigeminal nerve is responsible for facial sensory function, and trauma to this nerve can result in sudden, severe, stabbing and recurrent episodes of pain. Patients with TN experience a prolonged debilitating condition, where the pain is often described as one of the most painful conditions in medicine. TN is infamously called the “suicide disease” as there have been numerous suicide reports associated with the condition. Epidemiologists estimated the prevalence of chronic TN pain is also large at 7%3, which amounts to 36 million Europeans. Similarly, in the US, the American Association of Neurological Surgeons report that 150,000 people are diagnosed with TN every year with a prevalence of chronic TN impacting 1.7 % of population 4. Therefore in this proposal, we describe the development of a long-lasting and drug-free treatment for chronic Trigeminal Neuralgia.

Status

CLOSED

Call topic

ERC-2018-PoC

Update Date

27-04-2024
Images
No images available.
Geographical location(s)
Structured mapping
Unfold all
/
Fold all
Horizon 2020
H2020-EU.1. EXCELLENT SCIENCE
H2020-EU.1.1. EXCELLENT SCIENCE - European Research Council (ERC)
ERC-2018
ERC-2018-PoC