Summary
Although some biotechnologies have made huge strides e.g. in automation, data generation, or biochemical methods, cell
handling still uses antiquated methods that limit the scale at which assays can be performed. Our ERC-funded microfluidics
work has lead to cutting-edge microdroplet manipulation tools for cell handling: While working with 3D cell cultures, we
have recently shown that we can obtain great increases in both throughput and detail, while reducing the sample use and
the machine footprint. In addition to these quantitative leaps, the microfluidic format also allows qualitatively new biological
constructs to be explored by making significant steps towards the organ-on-a-chip framework. The current project therefore
aims to show how the technologies developed in our lab can function together in an integrated cell screening platform. This
will require demonstrating a convincing proof of concept of the hardware, software, and workflow, in addition to
demonstrating the added value to different industries.
handling still uses antiquated methods that limit the scale at which assays can be performed. Our ERC-funded microfluidics
work has lead to cutting-edge microdroplet manipulation tools for cell handling: While working with 3D cell cultures, we
have recently shown that we can obtain great increases in both throughput and detail, while reducing the sample use and
the machine footprint. In addition to these quantitative leaps, the microfluidic format also allows qualitatively new biological
constructs to be explored by making significant steps towards the organ-on-a-chip framework. The current project therefore
aims to show how the technologies developed in our lab can function together in an integrated cell screening platform. This
will require demonstrating a convincing proof of concept of the hardware, software, and workflow, in addition to
demonstrating the added value to different industries.
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More information & hyperlinks
| Web resources: | https://cordis.europa.eu/project/id/768790 |
| Start date: | 01-07-2017 |
| End date: | 31-12-2018 |
| Total budget - Public funding: | 150 000,00 Euro - 150 000,00 Euro |
Cordis data
Original description
Although some biotechnologies have made huge strides e.g. in automation, data generation, or biochemical methods, cellhandling still uses antiquated methods that limit the scale at which assays can be performed. Our ERC-funded microfluidics
work has lead to cutting-edge microdroplet manipulation tools for cell handling: While working with 3D cell cultures, we
have recently shown that we can obtain great increases in both throughput and detail, while reducing the sample use and
the machine footprint. In addition to these quantitative leaps, the microfluidic format also allows qualitatively new biological
constructs to be explored by making significant steps towards the organ-on-a-chip framework. The current project therefore
aims to show how the technologies developed in our lab can function together in an integrated cell screening platform. This
will require demonstrating a convincing proof of concept of the hardware, software, and workflow, in addition to
demonstrating the added value to different industries.
Status
CLOSEDCall topic
ERC-2017-PoCUpdate Date
27-04-2024
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