PARENT | PremAtuRe nEwborn motor and cogNitive impairmenTs: Early diagnosis

Summary
Prematurity exponentially increases the risk for an altered neurodevelopmental outcomes in childhood and adolescence. Many survivors children, face a lifetime of disability. Despite the advances in neonatal care have greatly improved survival of preterm born infants even at extremely low gestational ages we are now at a period of steadiness where no further improvement in long-term neurodevelopmental outcome is seen. The impact of these sequelae affects not only at a personal and familiar level but also poses a significant burden on society. Early diagnostics of brain injury and/or brain dysmaturation as well as early detection of impairments are important strategies to improve the well-being of children and their families allowing for developmental monitoring and medical evaluation of the specific type of disorder that affects a child and optimize therapeutics options.
In this context, PARENT is a vision for a multidisciplinary approach to develop diagnostic and predictive platforms focused on newborn motor/cognitive impairments. PARENT will make a critical contribution towards an open neurodevelopmental disease diagnostic software infrastructure by interlinking disciplines from clinical data, neuroimaging collection and processing, biomarkers, data fusion, machine learning applied to clinical data, novel prediction algorithms.
To best leverage the data potential, PARENT envisions an easy-to-use software infrastructure which provides integrated databases, validated algorithms components and platforms built upon them. This vision can be included in the more general paradigm of evidence-based medicine, personalized medicine and patient center care, as well as decision support systems in clinical field.
PARENT combines the efforts of a multidisciplinary network of 10 leading European research groups, industry partners, pediatric hospitals and parents’ association to develop a technological infrastructure that will train 15 Early Stage Researchers.
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More information & hyperlinks
Web resources: https://cordis.europa.eu/project/id/956394
Start date: 01-11-2020
End date: 30-04-2025
Total budget - Public funding: 3 835 853,28 Euro - 3 835 853,00 Euro
Cordis data

Original description

Prematurity exponentially increases the risk for an altered neurodevelopmental outcomes in childhood and adolescence. Many survivors children, face a lifetime of disability. Despite the advances in neonatal care have greatly improved survival of preterm born infants even at extremely low gestational ages we are now at a period of steadiness where no further improvement in long-term neurodevelopmental outcome is seen. The impact of these sequelae affects not only at a personal and familiar level but also poses a significant burden on society. Early diagnostics of brain injury and/or brain dysmaturation as well as early detection of impairments are important strategies to improve the well-being of children and their families allowing for developmental monitoring and medical evaluation of the specific type of disorder that affects a child and optimize therapeutics options.
In this context, PARENT is a vision for a multidisciplinary approach to develop diagnostic and predictive platforms focused on newborn motor/cognitive impairments. PARENT will make a critical contribution towards an open neurodevelopmental disease diagnostic software infrastructure by interlinking disciplines from clinical data, neuroimaging collection and processing, biomarkers, data fusion, machine learning applied to clinical data, novel prediction algorithms.
To best leverage the data potential, PARENT envisions an easy-to-use software infrastructure which provides integrated databases, validated algorithms components and platforms built upon them. This vision can be included in the more general paradigm of evidence-based medicine, personalized medicine and patient center care, as well as decision support systems in clinical field.
PARENT combines the efforts of a multidisciplinary network of 10 leading European research groups, industry partners, pediatric hospitals and parents’ association to develop a technological infrastructure that will train 15 Early Stage Researchers.

Status

SIGNED

Call topic

MSCA-ITN-2020

Update Date

28-04-2024
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Horizon 2020
H2020-EU.1. EXCELLENT SCIENCE
H2020-EU.1.3. EXCELLENT SCIENCE - Marie Skłodowska-Curie Actions (MSCA)
H2020-EU.1.3.1. Fostering new skills by means of excellent initial training of researchers
H2020-MSCA-ITN-2020
MSCA-ITN-2020