SELFIEv2.0 | Identifying the neuronal basis of self-concept in the human medial prefrontal and medial temporal brain regions

Summary
Humans have a remarkable ability to construct a complex conceptual representation of their own identity and personality. This self-concept plays a crucial role in everyday life; however, its neurobiological basis remains unknown. Here, we will use the state-of-the-art method of intracranial electroencephalography (iEEG) to characterize the neuronal representation of self-concept at the level of single-neurons in the medial prefrontal and medial temporal brain regions. IEEG will be recorded from awake human subjects, which is possible because a subset of neurosurgical patients requires placement of intracranial electrodes to identify the focus of epileptic seizures. We will conduct our studies during this monitoring time, with no added risk to the patients. Our data will provide unprecedented insights into the neuronal basis of the human self. Our findings will be of great interest to scientists in a broad range of disciplines, including neuroscience, psychology, artificial intelligence, neurology, psychiatry, as well as to the general public. The supervisors are world-leading experts in the neural self-representation (Prof. Ehrsson) and iEEG (Prof. Fried). Their laboratories conduct excellent research, as documented by multiple high-impact publications. The host institution (Karolinska Institute) and the partner institution (University of California, Los Angeles) are among the best universities in the world. Together, the fellowship provides an exceptional opportunity for the experienced researcher to become a leader in his field; he will learn the unique method of iEEG and he will collect the very first data on the neuronal basis of the conceptual self.
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More information & hyperlinks
Web resources: https://cordis.europa.eu/project/id/750955
Start date: 01-03-2018
End date: 28-02-2023
Total budget - Public funding: 265 059,00 Euro - 265 059,00 Euro
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Original description

Humans have a remarkable ability to construct a complex conceptual representation of their own identity and personality. This self-concept plays a crucial role in everyday life; however, its neurobiological basis remains unknown. Here, we will use the state-of-the-art method of intracranial electroencephalography (iEEG) to characterize the neuronal representation of self-concept at the level of single-neurons in the medial prefrontal and medial temporal brain regions. IEEG will be recorded from awake human subjects, which is possible because a subset of neurosurgical patients requires placement of intracranial electrodes to identify the focus of epileptic seizures. We will conduct our studies during this monitoring time, with no added risk to the patients. Our data will provide unprecedented insights into the neuronal basis of the human self. Our findings will be of great interest to scientists in a broad range of disciplines, including neuroscience, psychology, artificial intelligence, neurology, psychiatry, as well as to the general public. The supervisors are world-leading experts in the neural self-representation (Prof. Ehrsson) and iEEG (Prof. Fried). Their laboratories conduct excellent research, as documented by multiple high-impact publications. The host institution (Karolinska Institute) and the partner institution (University of California, Los Angeles) are among the best universities in the world. Together, the fellowship provides an exceptional opportunity for the experienced researcher to become a leader in his field; he will learn the unique method of iEEG and he will collect the very first data on the neuronal basis of the conceptual self.

Status

CLOSED

Call topic

MSCA-IF-2016

Update Date

28-04-2024
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Horizon 2020
H2020-EU.1. EXCELLENT SCIENCE
H2020-EU.1.3. EXCELLENT SCIENCE - Marie Skłodowska-Curie Actions (MSCA)
H2020-EU.1.3.2. Nurturing excellence by means of cross-border and cross-sector mobility
H2020-MSCA-IF-2016
MSCA-IF-2016