Summary
The survival of multicellular organisms requires inter-organ communication via long-distance signals. This is especially relevant in plants where post-embryonic development can be altered in response to sensing a heterogeneous nutrient environment in the soil. For example, a long-distance, inter-organ “root-shoot-root” relay system enables plant roots to specifically forage for nitrate-rich patches in a heterogeneous nutrient soil environment . In this proposal, I will use a unique “split-root” system to uncover the mechanisms of this systemic “root-shoot-root” relay system. Specifically, I will identify the targets of systemic N-signaling in plants as well as the potential RNA signals that traffic in phloem cells, the “information highway” to enable this inter-organ communication in plants. I will identify RNAs (mRNAs and smRNAs) associated with inter-organ signaling using a combination of time-based modeling and validate candidate genes using transgenics and shoot-root grafting. These studies will be the among the first to uncover systemic N-signals in a multicellular eukaryote.
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More information & hyperlinks
| Web resources: | https://cordis.europa.eu/project/id/659592 |
| Start date: | 01-09-2015 |
| End date: | 31-08-2018 |
| Total budget - Public funding: | 246 668,40 Euro - 246 668,00 Euro |
Cordis data
Original description
The survival of multicellular organisms requires inter-organ communication via long-distance signals. This is especially relevant in plants where post-embryonic development can be altered in response to sensing a heterogeneous nutrient environment in the soil. For example, a long-distance, inter-organ “root-shoot-root” relay system enables plant roots to specifically forage for nitrate-rich patches in a heterogeneous nutrient soil environment . In this proposal, I will use a unique “split-root” system to uncover the mechanisms of this systemic “root-shoot-root” relay system. Specifically, I will identify the targets of systemic N-signaling in plants as well as the potential RNA signals that traffic in phloem cells, the “information highway” to enable this inter-organ communication in plants. I will identify RNAs (mRNAs and smRNAs) associated with inter-organ signaling using a combination of time-based modeling and validate candidate genes using transgenics and shoot-root grafting. These studies will be the among the first to uncover systemic N-signals in a multicellular eukaryote.Status
CLOSEDCall topic
MSCA-IF-2014-GFUpdate Date
28-04-2024
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