Summary
How genome give rise to novel phenotypes is a major question in Biosciences. Transposable Elements (TEs) have co-evolved with host and are a major process by which organisms adapt to novel environments. Despite the discovery of the role of TEs in phenotypic innovations, the mechanisms and categories of TEs favoring their role in adaptive radiation remains elusive due to their repetitive nature. To palliate such lack of knowledge, I will take advantage of the new sequencing methodology providing chromosome length contigs, allowing to map precisely the different type of TEs, to sequence several cockroach species. Blattodea insect order is incredibly diverse and previous studies suggest the determinant role of TEs during Blattodea diversification, making it a perfect model to understand how and which TEs favor phenotypic innovations. I am particularly interested to investigate the role of TEs in the adaptation to wood feeding and sociality which led to the adaptive radiation of Blattodea species. My expertise in social evolution, its molecular basis and next-generation sequencing techniques, along with the computational expertise of Prof. Bornberg-Bauer lab will allow to detect the TE families responsible for the adaptation of specific phenotypes and as well by which mechanisms such phenotypes arise (e.g. chromosome rearrangement, gene duplication, regulation of gene expression). TEEPI will advance knowledge on the incredible role of TEs in the organismal adaptation to rapidly changing environments and may also provide a way to tame the expansion of cockroaches and termites, common pests that are on a rise with global warming. During TEEPI, I will gain scientific knowledge and transferable skills in computational biology such as genome assembly, and also on project management and outreach. This new skills are key to reach my career goal, which is to create my own research group on Insect Genomics, and also broaden my career perspective towards positions in industry.
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| Web resources: | https://cordis.europa.eu/project/id/101024100 |
| Start date: | 01-05-2021 |
| End date: | 30-04-2023 |
| Total budget - Public funding: | 174 806,40 Euro - 174 806,00 Euro |
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Original description
How genome give rise to novel phenotypes is a major question in Biosciences. Transposable Elements (TEs) have co-evolved with host and are a major process by which organisms adapt to novel environments. Despite the discovery of the role of TEs in phenotypic innovations, the mechanisms and categories of TEs favoring their role in adaptive radiation remains elusive due to their repetitive nature. To palliate such lack of knowledge, I will take advantage of the new sequencing methodology providing chromosome length contigs, allowing to map precisely the different type of TEs, to sequence several cockroach species. Blattodea insect order is incredibly diverse and previous studies suggest the determinant role of TEs during Blattodea diversification, making it a perfect model to understand how and which TEs favor phenotypic innovations. I am particularly interested to investigate the role of TEs in the adaptation to wood feeding and sociality which led to the adaptive radiation of Blattodea species. My expertise in social evolution, its molecular basis and next-generation sequencing techniques, along with the computational expertise of Prof. Bornberg-Bauer lab will allow to detect the TE families responsible for the adaptation of specific phenotypes and as well by which mechanisms such phenotypes arise (e.g. chromosome rearrangement, gene duplication, regulation of gene expression). TEEPI will advance knowledge on the incredible role of TEs in the organismal adaptation to rapidly changing environments and may also provide a way to tame the expansion of cockroaches and termites, common pests that are on a rise with global warming. During TEEPI, I will gain scientific knowledge and transferable skills in computational biology such as genome assembly, and also on project management and outreach. This new skills are key to reach my career goal, which is to create my own research group on Insect Genomics, and also broaden my career perspective towards positions in industry.Status
CLOSEDCall topic
MSCA-IF-2020Update Date
28-04-2024
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