GenDels | Development of a new CRISPR-Cas3-based tool for large genomic deletions

Summary
The advent of the revolutionary genome editing technique CRISPR-Cas9 has enabled targeted gene mutation, repression, and activation, facilitating impactful biological findings. However, Cas9 as an unbiased DNA deletion tool is limited in its ability to interrogate large regions of DNA of unknown function, because it predominantly generates very small (
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More information & hyperlinks
Web resources: https://cordis.europa.eu/project/id/844093
Start date: 01-07-2019
End date: 30-06-2022
Total budget - Public funding: 264 669,12 Euro - 264 669,00 Euro
Cordis data

Original description

The advent of the revolutionary genome editing technique CRISPR-Cas9 has enabled targeted gene mutation, repression, and activation, facilitating impactful biological findings. However, Cas9 as an unbiased DNA deletion tool is limited in its ability to interrogate large regions of DNA of unknown function, because it predominantly generates very small (

Status

CLOSED

Call topic

MSCA-IF-2018

Update Date

28-04-2024
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Structured mapping
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Horizon 2020
H2020-EU.1. EXCELLENT SCIENCE
H2020-EU.1.3. EXCELLENT SCIENCE - Marie Skłodowska-Curie Actions (MSCA)
H2020-EU.1.3.2. Nurturing excellence by means of cross-border and cross-sector mobility
H2020-MSCA-IF-2018
MSCA-IF-2018