Summary
The project CanBioSe targeted to strengthen international and intersectoral collaboration, sharing new ideas and
knowledge transfer from research to market and vice versa in the field of nanostructured metal oxide optical biosensors for
cancer cells detection. Interdisciplinary project research and innovation goals are targeted to develop a new portable tool for
early stage cancer detection which can solve on of important health challenges in EU society. One dimensional (1D) polimer
nanofibers will be deposited by electrospinning technique. Photonic nanomaterials, based on metal oxide based
nanostructures (ZnO, ZnO/Al2O3 nanolaminates, Au/ZnO and ZnO/Au) will coat the 1D nanofibers. Metal oxides and Au
nanoparticles will be deposited with Atomic Layer Deposition (ALD) and electrophoresis, respectively. Bioselective layer will
be formed by immobilization of specific antibodies on the biosensor surface. Photoluminescence and optical spectroscopy
will be used for recording of the biosensor signal. Biosensor testing will be performed on cancer cells (human chronic
lymphocyte leukemia (CLL) leucosis and acute lymphoblastic leucosis). The biosensor will be integrated with microfluidic
system in order to minimize dimensions and simplify the use of the detection system.
The project partners will provide research and training activities in the fields of nanotechnology, surface functionalization,
bioengineering, microfluidics and biosensor testing, market analysis and commercialization. Provided research and
management training to experienced researchers and early stage researchers will strengthen their personal skills and CVs
via new scientific papers and conference theses and strengthen a development of EU research human resources. Long
lasting collaboration between partners, based on co-supervising students and preparation of novel collaborative project
proposals is foreseen. Dissemination of the project results to scientific society and wide auditories is foreseen.
knowledge transfer from research to market and vice versa in the field of nanostructured metal oxide optical biosensors for
cancer cells detection. Interdisciplinary project research and innovation goals are targeted to develop a new portable tool for
early stage cancer detection which can solve on of important health challenges in EU society. One dimensional (1D) polimer
nanofibers will be deposited by electrospinning technique. Photonic nanomaterials, based on metal oxide based
nanostructures (ZnO, ZnO/Al2O3 nanolaminates, Au/ZnO and ZnO/Au) will coat the 1D nanofibers. Metal oxides and Au
nanoparticles will be deposited with Atomic Layer Deposition (ALD) and electrophoresis, respectively. Bioselective layer will
be formed by immobilization of specific antibodies on the biosensor surface. Photoluminescence and optical spectroscopy
will be used for recording of the biosensor signal. Biosensor testing will be performed on cancer cells (human chronic
lymphocyte leukemia (CLL) leucosis and acute lymphoblastic leucosis). The biosensor will be integrated with microfluidic
system in order to minimize dimensions and simplify the use of the detection system.
The project partners will provide research and training activities in the fields of nanotechnology, surface functionalization,
bioengineering, microfluidics and biosensor testing, market analysis and commercialization. Provided research and
management training to experienced researchers and early stage researchers will strengthen their personal skills and CVs
via new scientific papers and conference theses and strengthen a development of EU research human resources. Long
lasting collaboration between partners, based on co-supervising students and preparation of novel collaborative project
proposals is foreseen. Dissemination of the project results to scientific society and wide auditories is foreseen.
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More information & hyperlinks
| Web resources: | https://cordis.europa.eu/project/id/778157 |
| Start date: | 01-01-2018 |
| End date: | 31-12-2023 |
| Total budget - Public funding: | 1 116 000,00 Euro - 1 116 000,00 Euro |
Cordis data
Original description
The project CanBioSe targeted to strengthen international and intersectoral collaboration, sharing new ideas andknowledge transfer from research to market and vice versa in the field of nanostructured metal oxide optical biosensors for
cancer cells detection. Interdisciplinary project research and innovation goals are targeted to develop a new portable tool for
early stage cancer detection which can solve on of important health challenges in EU society. One dimensional (1D) polimer
nanofibers will be deposited by electrospinning technique. Photonic nanomaterials, based on metal oxide based
nanostructures (ZnO, ZnO/Al2O3 nanolaminates, Au/ZnO and ZnO/Au) will coat the 1D nanofibers. Metal oxides and Au
nanoparticles will be deposited with Atomic Layer Deposition (ALD) and electrophoresis, respectively. Bioselective layer will
be formed by immobilization of specific antibodies on the biosensor surface. Photoluminescence and optical spectroscopy
will be used for recording of the biosensor signal. Biosensor testing will be performed on cancer cells (human chronic
lymphocyte leukemia (CLL) leucosis and acute lymphoblastic leucosis). The biosensor will be integrated with microfluidic
system in order to minimize dimensions and simplify the use of the detection system.
The project partners will provide research and training activities in the fields of nanotechnology, surface functionalization,
bioengineering, microfluidics and biosensor testing, market analysis and commercialization. Provided research and
management training to experienced researchers and early stage researchers will strengthen their personal skills and CVs
via new scientific papers and conference theses and strengthen a development of EU research human resources. Long
lasting collaboration between partners, based on co-supervising students and preparation of novel collaborative project
proposals is foreseen. Dissemination of the project results to scientific society and wide auditories is foreseen.
Status
SIGNEDCall topic
MSCA-RISE-2017Update Date
28-04-2024
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Organisations
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| LATVIJAS UNIVERSITATE (Coördinator)
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| 3D STRONG, SIA
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| BIOSENSOR SRL
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| CSD HEALTH CARE
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| ECOLE NATIONALE SUPERIEURE DE CHIMIE DE MONTPELLIER
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| EESTI MATERJALITEHNOLOOGIATE ARENDUSKESKUSE OÜ
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| FONDAZIONE BRUNO KESSLER
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| Institute of Biophysics and Cell Engineering, National Academy of Sciences of Belarus
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| MATERIALS RESEARCH CENTER
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| MB SENSOGRAFA
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| NANO PRIME SPOLKA Z OGRANICZONA ODPOWIEDZIALNOSCIA
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| NANOPHARMA AS
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| STATE INSTITUTION REPUBLICAN SCIENTIFIC AND PRACTICAL CENTER FOR TRANSFUSIOLOGY AND MEDICAL BIOTECHN...
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| UNIWERSYTET IM. ADAMA MICKIEWICZA W POZNANIU
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| VILNIAUS UNIVERSITETAS