Summary
Despite their clear importance and potential to broadly influence host populations, little is known about pathogen interactions within a broader ecosystem. This project will use the well-studied Daphnia magna-Pasteuria ramosa host-parasite system as a model to investigate how various factors (temperature, route of transmission and selection for host resistance) interact to influence the repeatable seasonal epidemic dynamics observed in nature in order to further understand the ecological and evolutionary drivers of epidemics. The novelty offered by this project is that it will be using a combination of field observations, mesocosm and laboratory experiments along with mathematical modelling, aiming to quantify and measure the relative importance of factors that are often recognised to be important for epidemic dynamics, but not well understood. The originality offered by this project is that it will allow us to disentangle the complex relationships between hosts, parasites, the broader ecological community, and the abiotic environment and gain further insight to the rules that govern epidemic cycles and ecological feedback loops. By doing so, it allows to estimate the effect of climate change (in particular warmer summers) on the future dynamics of this host-parasite system. Understanding the drivers of infectious disease dynamics and the complex mechanisms of transmission and their relationship to the biotic and abiotic environment are more important than ever as we face the dual and linked challenges of global change and emerging infectious diseases.
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More information & hyperlinks
| Web resources: | https://cordis.europa.eu/project/id/101023370 |
| Start date: | 01-09-2021 |
| End date: | 31-08-2023 |
| Total budget - Public funding: | 191 149,44 Euro - 191 149,00 Euro |
Cordis data
Original description
Despite their clear importance and potential to broadly influence host populations, little is known about pathogen interactions within a broader ecosystem. This project will use the well-studied Daphnia magna-Pasteuria ramosa host-parasite system as a model to investigate how various factors (temperature, route of transmission and selection for host resistance) interact to influence the repeatable seasonal epidemic dynamics observed in nature in order to further understand the ecological and evolutionary drivers of epidemics. The novelty offered by this project is that it will be using a combination of field observations, mesocosm and laboratory experiments along with mathematical modelling, aiming to quantify and measure the relative importance of factors that are often recognised to be important for epidemic dynamics, but not well understood. The originality offered by this project is that it will allow us to disentangle the complex relationships between hosts, parasites, the broader ecological community, and the abiotic environment and gain further insight to the rules that govern epidemic cycles and ecological feedback loops. By doing so, it allows to estimate the effect of climate change (in particular warmer summers) on the future dynamics of this host-parasite system. Understanding the drivers of infectious disease dynamics and the complex mechanisms of transmission and their relationship to the biotic and abiotic environment are more important than ever as we face the dual and linked challenges of global change and emerging infectious diseases.Status
CLOSEDCall topic
MSCA-IF-2020Update Date
28-04-2024
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