TWINGOLD | Dinuclear Gold Catalysis: A New Platform for Cross-Coupling Reactions

Summary
Gold catalysis has become a powerful tool for organic chemists to streamline synthesis of valuable and complex molecules. Compared to other transition metals, gold complexes are remarkably stable towards air and water, and are essentially non-toxic, which make them ideal candidates to execute catalytic cross-coupling reactions in industry or in vivo. TWINGOLD aims at broadening the current applications of gold catalysis, exploring and identifying reliable dinuclear gold(I) catalysts in C-C forming reactions. The use of dinuclear gold catalysts could lower activation barriers of chemical transformations and thus allow access to reaction pathways that are difficult to accomplish with mononuclear gold systems. TWINGOLD will promote gold catalysis significantly by exploring novel cross-coupling reactions and the related mechanistic elements behind them, enabling use of more diverse raw materials and, thus, ensuring a more sustainable and inclusive economy in EU. In addition, the project will enable the Experienced Researcher to develop a full range of scientific and transferable skills following a personalized Career Development Plan to become an established researcher (R3).
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More information & hyperlinks
Web resources: https://cordis.europa.eu/project/id/792649
Start date: 03-01-2019
End date: 08-02-2021
Total budget - Public funding: 170 121,60 Euro - 170 121,00 Euro
Cordis data

Original description

Gold catalysis has become a powerful tool for organic chemists to streamline synthesis of valuable and complex molecules. Compared to other transition metals, gold complexes are remarkably stable towards air and water, and are essentially non-toxic, which make them ideal candidates to execute catalytic cross-coupling reactions in industry or in vivo. TWINGOLD aims at broadening the current applications of gold catalysis, exploring and identifying reliable dinuclear gold(I) catalysts in C-C forming reactions. The use of dinuclear gold catalysts could lower activation barriers of chemical transformations and thus allow access to reaction pathways that are difficult to accomplish with mononuclear gold systems. TWINGOLD will promote gold catalysis significantly by exploring novel cross-coupling reactions and the related mechanistic elements behind them, enabling use of more diverse raw materials and, thus, ensuring a more sustainable and inclusive economy in EU. In addition, the project will enable the Experienced Researcher to develop a full range of scientific and transferable skills following a personalized Career Development Plan to become an established researcher (R3).

Status

TERMINATED

Call topic

MSCA-IF-2017

Update Date

28-04-2024
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Horizon 2020
H2020-EU.1. EXCELLENT SCIENCE
H2020-EU.1.3. EXCELLENT SCIENCE - Marie Skłodowska-Curie Actions (MSCA)
H2020-EU.1.3.2. Nurturing excellence by means of cross-border and cross-sector mobility
H2020-MSCA-IF-2017
MSCA-IF-2017