Summary
The aim of this project is to use exchange of staff on an international and inter-sectoral basis to investigate the impact of consumption of novel nature-identical RRR-α-tocopherol in animal models on nutritional quality of animal-derived foods and in human models on bioavailability and circulating stereoisomers, and in doing so to foster a culture of research and innovation that will underpin new innovative products, services and processes in the area of animal and human nutrition. Vitamin E is represented by a suite of 8 compounds – 4 tocopherols (α, β, γ, δ) and 4 tocotrienols (α, β, γ, δ). The main function of vitamin E is as an anti-oxidant, preventing free radical-mediated lipid oxidation, particularly of membranal lipids. α-Tocopherol is the most biologically active form but α-tocopherol itself exists in 8 stereoisomeric forms arising from the 3 chiral centres it contains, RRR, RRS, RSR, RSS, SSS, SSR, SRS and SRR. Of these RRR-α-tocopherol is the most biologically active form.
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More information & hyperlinks
| Web resources: | https://cordis.europa.eu/project/id/778319 |
| Start date: | 01-09-2018 |
| End date: | 31-08-2022 |
| Total budget - Public funding: | 378 000,00 Euro - 378 000,00 Euro |
Cordis data
Original description
The aim of this project is to use exchange of staff on an international and inter-sectoral basis to investigate the impact of consumption of novel nature-identical RRR-α-tocopherol in animal models on nutritional quality of animal-derived foods and in human models on bioavailability and circulating stereoisomers, and in doing so to foster a culture of research and innovation that will underpin new innovative products, services and processes in the area of animal and human nutrition. Vitamin E is represented by a suite of 8 compounds – 4 tocopherols (α, β, γ, δ) and 4 tocotrienols (α, β, γ, δ). The main function of vitamin E is as an anti-oxidant, preventing free radical-mediated lipid oxidation, particularly of membranal lipids. α-Tocopherol is the most biologically active form but α-tocopherol itself exists in 8 stereoisomeric forms arising from the 3 chiral centres it contains, RRR, RRS, RSR, RSS, SSS, SSR, SRS and SRR. Of these RRR-α-tocopherol is the most biologically active form.Status
SIGNEDCall topic
MSCA-RISE-2017Update Date
28-04-2024
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