ICE-METs | Interstitium-on-a-chip to explore its role in cancer metastasis

Summary
The annual number of metastatic cancer deaths and the cost of cancer treatment makes cancer research a priority for the European Union. One of the key factors in metastatic cancer is the ability of the cancer cells to migrate from a primary tumor to the blood vessels and lymphatics. A better understanding of how cancer cells interact with the microenvironment and migrate from blood vessels to the lymphatics to create distant metastases, is key for discovering efficient chemotherapy drugs that will cover the growing needs of the worldwide population. The possibility of developing biomimetic engineered devices to understand metastasis proliferation and testing of drugs is a crucial goal for the research community, both in science and medicine, translating to major benefits for future patients. Therefore, the goal of the ICE-METs project is to deliver, a novel engineered microfluidic biomimetic platform to monitor the migration and proliferation of cancer cells in metastasis.
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More information & hyperlinks
Web resources: https://cordis.europa.eu/project/id/842356
Start date: 01-06-2019
End date: 31-05-2021
Total budget - Public funding: 212 933,76 Euro - 212 933,00 Euro
Cordis data

Original description

The annual number of metastatic cancer deaths and the cost of cancer treatment makes cancer research a priority for the European Union. One of the key factors in metastatic cancer is the ability of the cancer cells to migrate from a primary tumor to the blood vessels and lymphatics. A better understanding of how cancer cells interact with the microenvironment and migrate from blood vessels to the lymphatics to create distant metastases, is key for discovering efficient chemotherapy drugs that will cover the growing needs of the worldwide population. The possibility of developing biomimetic engineered devices to understand metastasis proliferation and testing of drugs is a crucial goal for the research community, both in science and medicine, translating to major benefits for future patients. Therefore, the goal of the ICE-METs project is to deliver, a novel engineered microfluidic biomimetic platform to monitor the migration and proliferation of cancer cells in metastasis.

Status

CLOSED

Call topic

MSCA-IF-2018

Update Date

28-04-2024
Geographical location(s)
Structured mapping
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EU-Programme-Call
Horizon 2020
H2020-EU.1. EXCELLENT SCIENCE
H2020-EU.1.3. EXCELLENT SCIENCE - Marie Skłodowska-Curie Actions (MSCA)
H2020-EU.1.3.2. Nurturing excellence by means of cross-border and cross-sector mobility
H2020-MSCA-IF-2018
MSCA-IF-2018