CARTHER | Carbon-based nano-materials for theranostic application

Summary
Our proposal aims to carry out a systematic interdisciplinary study of carbon-based nanomaterials, such as: carbon fluoroxide nanoparticles, carbon nanotubes, graphene and nanodiamonds for advanced theranostic application. Their uptake efficiency and specific localization in biological cells depending on intentionally designed surface chemistry will be studied in details. Extremely rich physico-chemical properties of the carbon-based nanomaterials will allow their application as multi-modal bio-imaging agents. Indeed, in addition to their well-known remarkable luminescent properties, two original bio-imaging approaches based on photo-induced electrical and acoustic effects will be developed in frames of our project. Moreover, the photo-exciting sources used for the bio-imaging purpose will be simultaneously used for therapy of cancer cells and tissues containing the carbon nanomaterials. Strongly complementary research experiences of the international partners involved in this project as well as high degree of cooperative integration between them will allow a deep scientific study of the theranostic potential of the carbon nanomaterials. Finally, active participation of the Ray Technique Ltd industrial company in the project consortium will allow building of strategies for economic realizations of the innovative achievements succeeded by the partners.
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More information & hyperlinks
Web resources: https://cordis.europa.eu/project/id/690945
Start date: 01-01-2016
End date: 31-12-2019
Total budget - Public funding: 891 000,00 Euro - 891 000,00 Euro
Cordis data

Original description

Our proposal aims to carry out a systematic interdisciplinary study of carbon-based nanomaterials, such as: carbon fluoroxide nanoparticles, carbon nanotubes, graphene and nanodiamonds for advanced theranostic application. Their uptake efficiency and specific localization in biological cells depending on intentionally designed surface chemistry will be studied in details. Extremely rich physico-chemical properties of the carbon-based nanomaterials will allow their application as multi-modal bio-imaging agents. Indeed, in addition to their well-known remarkable luminescent properties, two original bio-imaging approaches based on photo-induced electrical and acoustic effects will be developed in frames of our project. Moreover, the photo-exciting sources used for the bio-imaging purpose will be simultaneously used for therapy of cancer cells and tissues containing the carbon nanomaterials. Strongly complementary research experiences of the international partners involved in this project as well as high degree of cooperative integration between them will allow a deep scientific study of the theranostic potential of the carbon nanomaterials. Finally, active participation of the Ray Technique Ltd industrial company in the project consortium will allow building of strategies for economic realizations of the innovative achievements succeeded by the partners.

Status

CLOSED

Call topic

MSCA-RISE-2015

Update Date

28-04-2024
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Horizon 2020
H2020-EU.1. EXCELLENT SCIENCE
H2020-EU.1.3. EXCELLENT SCIENCE - Marie Skłodowska-Curie Actions (MSCA)
H2020-EU.1.3.3. Stimulating innovation by means of cross-fertilisation of knowledge
H2020-MSCA-RISE-2015
MSCA-RISE-2015