iTRUST | iTRUST: In-time TReatment of acUte ischaemic STroke

Summary
The problem: Intravenous thrombolysis is by far the most effective treatment of Acute Ischaemic Stroke (AIS), and its use can independently strongly increase the proportion of AIS patients surviving. However, in the emergency setting of AIS an excess of information must be considered by the physician including imaging, clinical presentation and electronic health record data before safely inferring on the suitability of thrombolytic therapy. Still, the therapeutic decision is largely dependent on the capacity of the expert radiologist in predicting what is the outcome for the given patient after applying the pharmacological treatment – a problem further compounded by the heterogeneity in AIS progression.

The solution: iTRUST solution is a clinical decision support system that uses Convolutional Neural Networks to predict the outcome of the AIS for each patient based on the patient’s biomarkers as well as clinical information. The prediction is presented as a probability of infarction when using pharmacological treatment or mechanical recanalization, making the prediction much more useful compared to current methods.

The market: The global AIS diagnosis and treatment market was valued at USD 1.2 billion in 2013 and is estimated to reach a market worth of USD 1.9 billion in 2020 growing at a CAGR of 6.3% from 2014 to 2020. Given the high incidence of AIS cases and the high importance of quickly allocating the appropriate therapeutic intervention, we have reasons to believe that iTRUST solution can generate an accumulated turnover exceeding EUR 32 million, five years post-project.
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More information & hyperlinks
Web resources: https://cordis.europa.eu/project/id/762947
Start date: 01-02-2017
End date: 31-07-2017
Total budget - Public funding: 71 429,00 Euro - 50 000,00 Euro
Cordis data

Original description

The problem: Intravenous thrombolysis is by far the most effective treatment of Acute Ischaemic Stroke (AIS), and its use can independently strongly increase the proportion of AIS patients surviving. However, in the emergency setting of AIS an excess of information must be considered by the physician including imaging, clinical presentation and electronic health record data before safely inferring on the suitability of thrombolytic therapy. Still, the therapeutic decision is largely dependent on the capacity of the expert radiologist in predicting what is the outcome for the given patient after applying the pharmacological treatment – a problem further compounded by the heterogeneity in AIS progression.

The solution: iTRUST solution is a clinical decision support system that uses Convolutional Neural Networks to predict the outcome of the AIS for each patient based on the patient’s biomarkers as well as clinical information. The prediction is presented as a probability of infarction when using pharmacological treatment or mechanical recanalization, making the prediction much more useful compared to current methods.

The market: The global AIS diagnosis and treatment market was valued at USD 1.2 billion in 2013 and is estimated to reach a market worth of USD 1.9 billion in 2020 growing at a CAGR of 6.3% from 2014 to 2020. Given the high incidence of AIS cases and the high importance of quickly allocating the appropriate therapeutic intervention, we have reasons to believe that iTRUST solution can generate an accumulated turnover exceeding EUR 32 million, five years post-project.

Status

CLOSED

Call topic

SMEInst-06-2016-2017

Update Date

27-10-2022
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Horizon 2020
H2020-EU.2. INDUSTRIAL LEADERSHIP
H2020-EU.2.1. INDUSTRIAL LEADERSHIP - Leadership in enabling and industrial technologies
H2020-EU.2.1.1. INDUSTRIAL LEADERSHIP - Leadership in enabling and industrial technologies - Information and Communication Technologies (ICT)
H2020-EU.2.1.1.0. INDUSTRIAL LEADERSHIP - ICT - Cross-cutting calls
H2020-SMEINST-1-2016-2017
SMEInst-06-2016-2017 Accelerating market introduction of ICT solutions for Health, Well-Being and Ageing Well
H2020-SMEINST-2-2016-2017
SMEInst-06-2016-2017 Accelerating market introduction of ICT solutions for Health, Well-Being and Ageing Well
H2020-EU.2.3. INDUSTRIAL LEADERSHIP - Innovation In SMEs
H2020-EU.2.3.1. Mainstreaming SME support, especially through a dedicated instrument
H2020-SMEINST-1-2016-2017
SMEInst-06-2016-2017 Accelerating market introduction of ICT solutions for Health, Well-Being and Ageing Well
H2020-SMEINST-2-2016-2017
SMEInst-06-2016-2017 Accelerating market introduction of ICT solutions for Health, Well-Being and Ageing Well
H2020-EU.3. SOCIETAL CHALLENGES
H2020-EU.3.1. SOCIETAL CHALLENGES - Health, demographic change and well-being
H2020-EU.3.1.4. Active ageing and self-management of health
H2020-EU.3.1.4.0. Cross-cutting call topics
H2020-SMEINST-1-2016-2017
SMEInst-06-2016-2017 Accelerating market introduction of ICT solutions for Health, Well-Being and Ageing Well
H2020-SMEINST-2-2016-2017
SMEInst-06-2016-2017 Accelerating market introduction of ICT solutions for Health, Well-Being and Ageing Well
H2020-EU.3.1.6. Health care provision and integrated care
H2020-EU.3.1.6.0. Cross-cutting call topics
H2020-SMEINST-1-2016-2017
SMEInst-06-2016-2017 Accelerating market introduction of ICT solutions for Health, Well-Being and Ageing Well
H2020-SMEINST-2-2016-2017
SMEInst-06-2016-2017 Accelerating market introduction of ICT solutions for Health, Well-Being and Ageing Well