VALORISH | Green VALORisation cascade approach of fISH waste and by-products through fermentation towards a zero-waste future

Summary
VALORISH is a 42-month action that aims to develop a computationally-assisted methodology for the design and implementation of a biorefinery with a cascade approach to valorise waste and by-products from the fishing industry at TRL 5. The target portfolio of products will be fish oil, fish protein hydrolysates, bacteriocins, pigments, vitamins, collagen and calcium-rich powder, targeting food products, additives, supplements and nutraceuticals. The cascade conversion processes will vary with the feedstock heterogeneity, comprising pre-treatment, oil green extraction, proteolytic fermentation (protein hydrolysis), fermentation with hydrolysates as substrate, and a portfolio of downstream processes. The proteolytic fermentation will be guided by computational biology, using models to search new candidate enzyme-producing bacteria. The fish protein hydrolysates obtained in the fermentation will be used, first, as food supplement due to their bioactive properties, and second, as substrate for supporting a second fermentation, to obtain high-value bioproducts, namely bacteriocins and astaxanthin, as food additives, and vitamin B12, as food supplement. Novel genome-scale metabolic models will be used to link substrate composition to the desired bioproducts via inspection of metabolic pathways and selecting optimal microorganisms. In a zero-waste aim, the fermentation side-streams will be valorised (bones by extraction and calcination, and residual biomass by anaerobic digestion). All the bioproducts will be analysed for chemical, nutritional, bioactive and safety properties to comply with EU regulation, and will be included in food/nutraceutical formulations and validated by end users. A mathematical model will be developed to simulate the biorefinery and to support the satisfactory scale-up of the core processes as well as the assessment methodologies (technoeconomic, environmental, standardisation). Social impact and acceptance of the products will be also assessed.
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More information & hyperlinks
Web resources: https://cordis.europa.eu/project/id/101135078
Start date: 01-05-2024
End date: 31-10-2027
Total budget - Public funding: 3 935 845,00 Euro - 3 935 845,00 Euro
Cordis data

Original description

VALORISH is a 42-month action that aims to develop a computationally-assisted methodology for the design and implementation of a biorefinery with a cascade approach to valorise waste and by-products from the fishing industry at TRL 5. The target portfolio of products will be fish oil, fish protein hydrolysates, bacteriocins, pigments, vitamins, collagen and calcium-rich powder, targeting food products, additives, supplements and nutraceuticals. The cascade conversion processes will vary with the feedstock heterogeneity, comprising pre-treatment, oil green extraction, proteolytic fermentation (protein hydrolysis), fermentation with hydrolysates as substrate, and a portfolio of downstream processes. The proteolytic fermentation will be guided by computational biology, using models to search new candidate enzyme-producing bacteria. The fish protein hydrolysates obtained in the fermentation will be used, first, as food supplement due to their bioactive properties, and second, as substrate for supporting a second fermentation, to obtain high-value bioproducts, namely bacteriocins and astaxanthin, as food additives, and vitamin B12, as food supplement. Novel genome-scale metabolic models will be used to link substrate composition to the desired bioproducts via inspection of metabolic pathways and selecting optimal microorganisms. In a zero-waste aim, the fermentation side-streams will be valorised (bones by extraction and calcination, and residual biomass by anaerobic digestion). All the bioproducts will be analysed for chemical, nutritional, bioactive and safety properties to comply with EU regulation, and will be included in food/nutraceutical formulations and validated by end users. A mathematical model will be developed to simulate the biorefinery and to support the satisfactory scale-up of the core processes as well as the assessment methodologies (technoeconomic, environmental, standardisation). Social impact and acceptance of the products will be also assessed.

Status

SIGNED

Call topic

HORIZON-CL6-2023-CircBio-02-3-two-stage

Update Date

21-11-2024
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Horizon Europe
HORIZON.2 Global Challenges and European Industrial Competitiveness
HORIZON.2.6 Food, Bioeconomy Natural Resources, Agriculture and Environment
HORIZON.2.6.0 Cross-cutting call topics
HORIZON-CL6-2023-CIRCBIO-02
HORIZON-CL6-2023-CircBio-02-3-two-stage Non-plant biomass feedstock for industrial applications: technologies and processes to convert non-lignocellulosic biomass and waste into bio-based chemicals, materials and products, improving the cascading valorisation of biomass