arrayed surveillance | Glyco-protein arrays for functional virus surveillance

Summary
This ERC PoC project aims to establish the technical and commercial feasibility of our recently developed glycan-arrays in which we determined the minimal receptor for duck, chicken, and human influenza A viruses, respectively. We also determined structures vital for viruses as intermediate receptors on the avian-mammalian interface. With our experience in printing arrays, we also want to add proteinaceous receptors for coronaviruses. This mixed “glyco-protein” array will then be employed for functional surveillance of two virus families with significant pandemic threat. The ERC program “sugar-enable” has developed different glycan arrays that should be used in the real world to detect potential pandemic viruses as soon as possible, now making a substantial societal impact. In this project, we aim to conduct a technical and commercial feasibility study.
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More information & hyperlinks
Web resources: https://cordis.europa.eu/project/id/101183378
Start date: 01-08-2024
End date: 31-01-2026
Total budget - Public funding: - 150 000,00 Euro
Cordis data

Original description

This ERC PoC project aims to establish the technical and commercial feasibility of our recently developed glycan-arrays in which we determined the minimal receptor for duck, chicken, and human influenza A viruses, respectively. We also determined structures vital for viruses as intermediate receptors on the avian-mammalian interface. With our experience in printing arrays, we also want to add proteinaceous receptors for coronaviruses. This mixed “glyco-protein” array will then be employed for functional surveillance of two virus families with significant pandemic threat. The ERC program “sugar-enable” has developed different glycan arrays that should be used in the real world to detect potential pandemic viruses as soon as possible, now making a substantial societal impact. In this project, we aim to conduct a technical and commercial feasibility study.

Status

SIGNED

Call topic

ERC-2024-POC

Update Date

29-09-2024
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Horizon Europe
HORIZON.1 Excellent Science
HORIZON.1.1 European Research Council (ERC)
HORIZON.1.1.1 Frontier science
ERC-2024-POC ERC PROOF OF CONCEPT GRANTS