Summary
Over the past two decades, the pharmaceutical industry has witnessed an exponential growth in approved covalent drugs. The majority of such drugs incorporate a chemical warhead, a mild electrophilic reactive functional group that forms covalent bonds in a reversible or irreversible manner with nucleophilic aminoacid residues. The aim of this proposal is to assess the viability of a new chemical warhead in the discovery of novel kinase inhibitors.
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| Web resources: | https://cordis.europa.eu/project/id/101189468 |
| Start date: | 01-11-2024 |
| End date: | 30-04-2026 |
| Total budget - Public funding: | - 150 000,00 Euro |
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Original description
Over the past two decades, the pharmaceutical industry has witnessed an exponential growth in approved covalent drugs. The majority of such drugs incorporate a chemical warhead, a mild electrophilic reactive functional group that forms covalent bonds in a reversible or irreversible manner with nucleophilic aminoacid residues. The aim of this proposal is to assess the viability of a new chemical warhead in the discovery of novel kinase inhibitors.Status
SIGNEDCall topic
ERC-2024-POCUpdate Date
21-11-2024
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