RELAI | Regenerative Engineering of Living Autologous Interfaces

Summary
RELAI will design and exploit a toolbox of innovative bioelectronic technologies and surgical constructs that will enable new possibilities in neural interfacing and revolutionise the way we transduce information to and from the human body. This new class of living bioelectronics will leverage bespoke electrode arrays and electrical stimulation paradigms to guide neural regeneration within autologous surgical constructs in vivo. The reinnervated constructs are hypothesised to form living high-resolution interfaces that will enable precise modulation of somatic and autonomic functions via injured and intact nerves. This innovative class of biohybrid interfaces will enable a broad array of applications ranging from the treatment of chronic conditions (such as diabetes) to the enhanced operation of advanced neuroprostheses, and the realisation of supraphysiological sensing.
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More information & hyperlinks
Web resources: https://cordis.europa.eu/project/id/101189526
Start date: 01-01-2025
End date: 30-06-2026
Total budget - Public funding: - 150 000,00 Euro
Cordis data

Original description

RELAI will design and exploit a toolbox of innovative bioelectronic technologies and surgical constructs that will enable new possibilities in neural interfacing and revolutionise the way we transduce information to and from the human body. This new class of living bioelectronics will leverage bespoke electrode arrays and electrical stimulation paradigms to guide neural regeneration within autologous surgical constructs in vivo. The reinnervated constructs are hypothesised to form living high-resolution interfaces that will enable precise modulation of somatic and autonomic functions via injured and intact nerves. This innovative class of biohybrid interfaces will enable a broad array of applications ranging from the treatment of chronic conditions (such as diabetes) to the enhanced operation of advanced neuroprostheses, and the realisation of supraphysiological sensing.

Status

SIGNED

Call topic

ERC-2024-POC

Update Date

25-11-2024
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Horizon Europe
HORIZON.1 Excellent Science
HORIZON.1.1 European Research Council (ERC)
HORIZON.1.1.1 Frontier science
ERC-2024-POC ERC PROOF OF CONCEPT GRANTS