NAOS | a disruptive implantable neurostimulator for the treatment of epilepsy

Summary
The objective of this innovation project is to develop a disruptive implantable neurostimulator for the treatment of epilepsy with the
goal to place it on the market by 2021.

Neurostimulation is a $4.7 billion market and one of the fastest-growing areas of medicine, that has been approved for the treatment
of several neurological disorders. Among these, epilepsy is the most frequent nervous system disease. Of the 50 million people
suffering from epilepsy, with 3.7 million in Europe, approximately one third of them are resistant to medication but respond well to
the neurostimulation.

Neurostimulators are small implanted devices stimulating nerves or brain tissue. The innovative aspects of the project are based on a
Synergia Medical’s patented concept and consists in replacing wires by optical fibres.

The innovation will improve the traditional therapy and brings the main following competitive advantages:
- it renders the neurostimulator compatible with magnetic resonance imaging (MRI) diagnosis
- it provides a highly tunable stimulation and ultra low power consumption
- it improves safety due to electrical isolation and allow for a smaller size implant

The main objective of this feasibility study is to complete the business plan by:
- completing a market study and refining specifications of the neurostimulator with key opinion leaders in the field of epilepsy;
- manufacturing prototypes of neurostimulators to validate stimulation capabilities, low power consumption, compactness, optical
chain efficiency and estimate production costs;
- refining the development and production planning, including budget and human resources, based on cost estimates and test
results;
- finalizing the selection of subcontractors involved in the production chain;
- filing additional patents and realizing a complete FTO.
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More information & hyperlinks
Web resources: https://cordis.europa.eu/project/id/875931
Start date: 01-07-2019
End date: 30-11-2019
Total budget - Public funding: 71 429,00 Euro - 50 000,00 Euro
Cordis data

Original description

The objective of this innovation project is to develop a disruptive implantable neurostimulator for the treatment of epilepsy with the
goal to place it on the market by 2021.

Neurostimulation is a $4.7 billion market and one of the fastest-growing areas of medicine, that has been approved for the treatment
of several neurological disorders. Among these, epilepsy is the most frequent nervous system disease. Of the 50 million people
suffering from epilepsy, with 3.7 million in Europe, approximately one third of them are resistant to medication but respond well to
the neurostimulation.

Neurostimulators are small implanted devices stimulating nerves or brain tissue. The innovative aspects of the project are based on a
Synergia Medical’s patented concept and consists in replacing wires by optical fibres.

The innovation will improve the traditional therapy and brings the main following competitive advantages:
- it renders the neurostimulator compatible with magnetic resonance imaging (MRI) diagnosis
- it provides a highly tunable stimulation and ultra low power consumption
- it improves safety due to electrical isolation and allow for a smaller size implant

The main objective of this feasibility study is to complete the business plan by:
- completing a market study and refining specifications of the neurostimulator with key opinion leaders in the field of epilepsy;
- manufacturing prototypes of neurostimulators to validate stimulation capabilities, low power consumption, compactness, optical
chain efficiency and estimate production costs;
- refining the development and production planning, including budget and human resources, based on cost estimates and test
results;
- finalizing the selection of subcontractors involved in the production chain;
- filing additional patents and realizing a complete FTO.

Status

CLOSED

Call topic

EIC-SMEInst-2018-2020

Update Date

27-10-2022
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Horizon 2020
H2020-EU.2. INDUSTRIAL LEADERSHIP
H2020-EU.2.1. INDUSTRIAL LEADERSHIP - Leadership in enabling and industrial technologies
H2020-EU.2.1.0. INDUSTRIAL LEADERSHIP - Leadership in enabling and industrial technologies - Cross-cutting calls
H2020-EIC-SMEInst-2018-2020
H2020-SMEInst-2018-2020-1
H2020-EU.2.3. INDUSTRIAL LEADERSHIP - Innovation In SMEs
H2020-EU.2.3.0. INDUSTRIAL LEADERSHIP - Innovation In SMEs - Cross-cutting calls
H2020-EIC-SMEInst-2018-2020
H2020-SMEInst-2018-2020-1
H2020-EU.3. SOCIETAL CHALLENGES
H2020-EU.3.0. Cross-cutting call topics
H2020-EIC-SMEInst-2018-2020
H2020-SMEInst-2018-2020-1