PEROXIS ground-breaking PEROvskite technologies for advanced X-ray medical Imaging Systems

Summary

The PEROXIS project will develop a new X-ray imaging system with higher sensitivity and spatial resolution compared to conventional ones, which will support diagnosis during intervention and treatments of various diseases.
The emerging semiconducting perovskite materials, largely used for photovoltaic applications, are a good candidate since they have the potential to globally address the following ambitious objectives:
-Advancing X-ray based imaging systems for advanced diagnostics and treatments of two major diseases: cardiovascular disease (CVD) and chronic obstructive pulmonary disease (COPD)
-Improving the efficiency and spatial resolution of flat panel X-ray detectors
-Groundbreaking perovskite-based direct conversion X-ray imaging detectors for large-area compatibility
-Validating the feasibility of phase contrast imaging for earlier detection of chronic obstructive pulmonary disease
PEROXIS is a multidisciplinary project engaging 7 EU partners from 4 countries (France, Germany, Spain and the Netherlands) covering the academic, RTO and industrial (3 major medical equipment manufacturers) worlds. An implementation plan is presented in the form of 8 work packages, 6 of which are technical in nature. Synergy in communication and dissemination by the several partners and stakeholders (external advisory board mainly composed of physicians who provide letters of intent) will permit to maximize the PEROXIS project impact.
Both solutions to overcome the fundamental technological barriers as well as appropriate deliverables, tasks, milestones and risks in order to complete the project objectives in due time are presented. The medical sector will be highly impacted by the PEROXIS project outcome: future applications of an improved PEROXIS imaging system will not be limited to COPD and CVD only, but may be extended to various other clinical domains in which the performance of diagnostic driven therapy systems is limited by current flat panel X-ray detector technology.

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Web resources:	https://cordis.europa.eu/project/id/871336
Start date:	01-01-2020
End date:	31-12-2023
Total budget - Public funding:	5 977 498,00 Euro - 5 977 498,00 Euro

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Original description

The PEROXIS project will develop a new X-ray imaging system with higher sensitivity and spatial resolution compared to conventional ones, which will support diagnosis during intervention and treatments of various diseases.
The emerging semiconducting perovskite materials, largely used for photovoltaic applications, are a good candidate since they have the potential to globally address the following ambitious objectives:
-Advancing X-ray based imaging systems for advanced diagnostics and treatments of two major diseases: cardiovascular disease (CVD) and stroke
-Improving the efficiency and spatial resolution of flat panel X-ray detectors
-Groundbreaking perovskite-based direct conversion X-ray imaging detectors for large-area compatibility
-Validating the improved image quality of cone beam computed tomography (CBCT) in stroke detection
PEROXIS is a multidisciplinary project engaging 7 EU partners from 4 countries (France, Germany, Spain and the Netherlands) covering the academic, RTO and industrial (3 major medical equipment manufacturers) worlds. An implementation plan is presented in the form of 8 work packages, 6 of which are technical in nature. Synergy in communication and dissemination by the several partners and stakeholders (external advisory board mainly composed of physicians who provide letters of intent) will permit to maximize the PEROXIS project impact.
Both solutions to overcome the fundamental technological barriers as well as appropriate deliverables, tasks, milestones and risks in order to complete the project objectives in due time are presented. The medical sector will be highly impacted by the PEROXIS project outcome: future applications of an improved PEROXIS imaging system will not be limited to stroke and CVD only, but may be extended to various other clinical domains in which the performance of diagnostic driven therapy systems is limited by current flat panel X-ray detector technology.