Periodic Reporting for period 4 - SVDs-at-target (Small vessel diseases in a mechanistic perspective: Targets for InterventionAffected pathways and mechanistic exploitation for prevention of stroke and dementia)

Cerebral small vessel disease (SVD) is a major cause of stroke, disability and dementia. It is caused by a dysfunction of the small arteries, which supply blood to the deep brain regions. Smooth muscle cells (SMC) that surround the vessels regulate blood flow and ensure a...