Summary
Our study is well powered to detect the ~42% reduction in risk predicted from our studies of family-based intervention in the UK, and the effect sizes for reduction of risk of T2D observed in published studies of lifestyle modification vs usual care for prevention of T2D (30-60%).
The analysis committee will be responsible for data monitoring during the study, for the primary and secondary analyses of the study endpoints, and for assisting the consortium prepare technical reports for dissemination of the research findings.
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