Report on Intervention

With a sample size of 3,600 we therefore expect to identify up ~734 cases of new onset T2D over three years under the null hypothesis. Assuming a 10% dropout rate , with a 1:1 allocation ratio, a total of 120 clusters each of size 30, our study has 80% power to identify at P<0.017, a reduction in the incidence of T2D for family-based lifestyle modification vs usual care.