Markers and cellular responses in OA osteochondral units

This deliverable will associate in vitro analysis with in vivo assessments on the basis of matching imaging and biomarkers results. Furthermore, this deliverable will provide a dataset including cartilage and bone soluble markers, microCT imaging of bone and cartilage, cellular response by qRT-PCR, histology and immunohistochemistry that will be used for the generation of the multiscale hypermodel.