Structure-guided multivalent nanobodies block SARS-CoV-2 infection and suppress mutational escape

Summary

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Authors: Paul-Albert Koenig, Hrishikesh Das, Hejun Liu, Beate M. Kümmerer, Florian N. Gohr, Lea-Marie Jenster, Lisa D. J. Schiffelers, Yonas M. Tesfamariam, Miki Uchima, Jennifer D. Wuerth, Karl Gatterdam, Natalia Ruetalo, Maria H. Christensen, Caroline I. Fandrey, Sabine Normann, Jan M. P. Tödtmann, Steffen Pritzl, Leo Hanke, Jannik Boos, Meng Yuan, Xueyong Zhu, Jonathan L. Schmid-Burgk, Hiroki Kato, Mi

Journal title: Science

Journal number: 371/6530

Journal publisher: American Association for the Advancement of Science

Published year: 2021

Published pages: eabe6230

DOI identifier: 10.1126/science.abe6230

ISSN: 0036-8075