DFG-1 Residue Controls Inhibitor Binding Mode and Affinity, Providing a Basis for Rational Design of Kinase Inhibitor Selectivity

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Authors: Martin Schröder, Alex N. Bullock, Oleg Fedorov, Franz Bracher, Apirat Chaikuad, Stefan Knapp

Journal title: Journal of Medicinal Chemistry

Journal number: 63/18

Journal publisher: American Chemical Society

Published year: 2020

Published pages: 10224-10234

DOI identifier: 10.1021/acs.jmedchem.0c00898

ISSN: 0022-2623