Amide-to-ester substitution as a strategy for optimizing PROTAC permeability and cellular activity

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Authors: Victoria G. Klein; Adam G. Bond; Conner Craigon; R. Scott Lokey; Alessio Ciulli

Journal title: Journal of Medicinal Chemistry

Journal number: 2

Journal publisher: American Chemical Society

Published year: 2021

DOI identifier: 10.1021/acs.jmedchem.1c01496

ISSN: 0002-7863