Periodic Reporting for period 4 - PACE (A multicenter phase IIb study using HLA-unmatched allogeneic placenta-derived stromal cells (PLX-PAD) for the treatment of severe critical limb ischemia accompanied by mechanistic studies)

What is the problem/issue being addressed? Critical limb ischemia (CLI) is at the severe end of peripheral artery disease (PAD) spectrum when limb perfusion is reduced to tissue loss. Nutrient blood flow to the tissues and microcirculation exchange are seriously affected. As...