Microglial signalling pathway deficits associated with the patient derived R47H TREM2 variants linked to AD indicate inability to activate inflammasome

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Authors: Katharina Cosker, Anna Mallach, Janhavi Limaye, Thomas M. Piers, James Staddon, Stephen J. Neame, John Hardy & Jennifer M. Pocock

Journal title: Scientific Reports

Journal publisher: Nature Publishing Group

Published year: 2021

DOI identifier: 10.1038/s41598-021-91207-1

ISSN: 2045-2322